Results 161 to 170 of about 358,324 (325)
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Global health and the dialectics of solidarity through Ubuntu and European perspectives. [PDF]
Anyikwa CL.
europepmc +1 more source
Explaining the wage gap: Heckscher-Ohlin, economic geography and services availability [PDF]
In the debate on globalisation and wage inequality Heckscher-Ohlin, economic geography and services availability theory has featured prominently. However, a neglected mechanism by which globalisation affects labour market outcomes is through the in ...
Peeters, J., Vaal, A. de
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Global research agenda for medical education regulation: findings from a nominal group consensus exercise. [PDF]
Bollela VR +17 more
europepmc +1 more source
Globalisation and Social Spending [PDF]
We provide evidence indicating that countries with well-developed social security systems do not necessarily face a trade-off between social spending and competitiveness.
Magdalena Polan, Paul De Grauwe
core
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source

