Results 61 to 70 of about 358,324 (325)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Die gewerblichen Fortbildungsschulen in den Provinzen Posen und Westpreußen. Instrumente der Polenpolitik, Vorreiter des Staatsschulsystems und Elemente regionaler Entwicklungspolitik

open access: yesStudia Historiae Oeconomicae, 2009
Stefan Kowal hat mehrfach auf das im Vergleich zu Deutschen und Juden geringere Bildungsniveau der polnischen Bevölkerung in den preußischen Ost- provinzen hingewiesen. Dieser Rückstand resultierte aus den gerade auch von Stefan Kowal herausgearbeiteten,
Uwe Müller
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Constructing democratic participation in welfare transitions: An analysis of narrative interactions

open access: yesHealth Expectations, 2020
Objective This article provides insights into the democratic character of local enactments of welfare reforms by analysing narrative interactions about changes in care.
Mare Knibbe, Klasien Horstman
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Reflections on globalisation, security and 9/11 [PDF]

open access: yes, 2002
The study of globalisation carries important conceptual insights into the contemporary security agenda following the events of September 11th 2001 ('9/11').
Hughes, Christopher W.
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Violent Jihad and Beheadings in the Land of Al Fatoni Darussalam

open access: yesReligions, 2015
The early 2000s has seen a revival of the Patani resistance manifesting in a violent jihad and new forms of extreme violence never witnessed before in the century-long Southern Thailand conflict. Transported by neojihadism, this new energised generation
Virginie Andre
doaj   +1 more source

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