Results 71 to 80 of about 77,983 (316)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Dis:connectivity and Globalisation

open access: yes
The volume explores key concepts that illuminate globalisation from a dis:connective perspective. Dis:connectivity refers to a more complex understanding of globalization that encompasses both connectivity as well as disruption, delay and deceleration ...

core   +1 more source

Globalisation and Inequality

open access: yesMillennium: Journal of International Studies, 1995
Neglected in liberal and other writings about globalisation is one particularly important feature of world politics: inequality. This chapter highlights the relationship between globalisation and inequality. It argues that inequality matters not just on grounds of equity, but is also important for understanding the nature of globalisation and its ...
Hurrell, A, Woods, N
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Die gewerblichen Fortbildungsschulen in den Provinzen Posen und Westpreußen. Instrumente der Polenpolitik, Vorreiter des Staatsschulsystems und Elemente regionaler Entwicklungspolitik

open access: yesStudia Historiae Oeconomicae, 2009
Stefan Kowal hat mehrfach auf das im Vergleich zu Deutschen und Juden geringere Bildungsniveau der polnischen Bevölkerung in den preußischen Ost- provinzen hingewiesen. Dieser Rückstand resultierte aus den gerade auch von Stefan Kowal herausgearbeiteten,
Uwe Müller
doaj   +1 more source

Can performance of indigenous factors influence growth and globalisation? [PDF]

open access: yes, 2007
This paper employs a total of thirty four openness factors and indigenous factors to construct two indicators for 62 world economies for the period 1998-2002.
Li, KW   +8 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Constructing democratic participation in welfare transitions: An analysis of narrative interactions

open access: yesHealth Expectations, 2020
Objective This article provides insights into the democratic character of local enactments of welfare reforms by analysing narrative interactions about changes in care.
Mare Knibbe, Klasien Horstman
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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