Results 91 to 100 of about 6,311,719 (382)
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Turning inside out?: Globalization, neo-liberalism and welfare states
Apocalyptic accounts of globalization bringing about the end of the welfare state (and the nation state) have been countered by political-institutionalist views of adaptation. Such views treat globalization as an external force, or pressure, rather than
Clarke, John
core +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
How do undocumented migrants maintain different degrees of visibility in public space? How does public visibility affect the livelihood strategies of undocumented migrants?
Theodore Baird
doaj +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
Method Factors in Democracy Indicators
Method factors represent variance common to indicators from the same data source. Detecting method factors can help uncover systematic bias in data sources.
Martin Elff, Sebastian Ziaja
doaj +1 more source
Globalization and Economic Growth: Empirical Evidence on the Role of Complementarities
This study was carried out to investigate the effect of economic globalization on economic growth in OIC countries. Furthermore, the study examined the effect of complementary policies on the growth effect of globalization.
P. Samimi, H. S. Jenatabadi
semanticscholar +1 more source
Global Challenges, Global Opportunities
Academia is at an exciting crossroads. The global problems we face are immense, but the good news is we know how to address most of them. Our primary challenge today is not a lack of knowledge but a failure to scale up what we already know works. Some of the skills to implement what we know are medical, many are not.
openaire +5 more sources