Results 111 to 120 of about 1,153,486 (198)

When Words Matter: Language Choices and Brand Building on Two Global Coffee Shop Retail Brands in Indonesia [PDF]

, 2021
Jovid Jonathan Latukolan, Rustono Farady Marta, Engliana Engliana   +2 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013

, 2016
Hmwe Hmwe Kyu, Christine Pinho, Joseph A. Wagner, Jonathan C. Brown, Amelia Bertozzi-Villa, Fiona Charlson, Luc E. Coffeng, Lalit Dandona, Holly E Erskine, Alize J Ferrari, Christina Fitzmaurice, Thomas Fleming, Mohammad H. Forouzanfar, Nicholas Graetz, Caterina Guinovart, Juanita A. Haagsma, Hideki Higashi, Nicholas J Kassebaum, Heidi J. Larson, Stephen S Lim, Ali H. Mokdad, Maziar Moradi‐Lakeh, Shaun V. Odell, Gregory A. Roth, Peter Serina, Jeffrey D Stanaway, Awoke Misganaw, Harvey Whiteford, Timothy M Wolock, Sarah Wulf Hanson, Foad Abd-Allah, Semaw Ferede Abera, Laith J. Abu‐Raddad, Fadia AlBuhairan, Azmeraw T. Amare, Carl Abelardo T. Antonio, Al Artaman, Suzanne Barker‐Collo, Lope H. Barrero, Corina Benjet, Isabela M. Benseñor, Zulfiqar A Bhutta, Boris Bikbov, Alexandra Bražinová, Ismael Campos‐Nonato, Carlos A Castañeda-Orjuela, Ferrán Catalá-López, Rajiv Chowdhury, Cyrus Cooper, John A. Crump, Rakhi Dandona, Louisa Degenhardt, Robert P Dellavalle, Samath Dhamminda Dharmaratne, Emerito Jose A Faraon, Valery L. Feigin, Thomas Fürst, Johanna M. Geleijnse, Bradford D. Gessner, Katherine B. Gibney, Atsushi Goto, David Gunnell, Graeme J. Hankey, Roderick J. Hay, John Hornberger, Hung Chak Ho, Guoqing Hu, Kathryn H. Jacobsen, Sudha Jayaraman, Panniyammakal Jeemon, Jost B. Jonas, Andrè Karch, Daniel Kim, Sungroul Kim, Yoshihiro Kokubo, Barthélémy Kuate Defo, Burcu Küçük Biçer, G Anil Kumar, Anders Larsson, Janet L Leasher, Ricky Leung, Yongmei Li, Steven E. Lipshultz, Alan D López, Paulo A. Lotufo, Raimundas Lunevičius, Ronan A Lyons, Marek Majdán, Reza Malekzadeh, Taufiq Mashal, Amanda J. Mason‐Jones, Yohannes Adama Melaku, Ziad A. Memish, Walter Mendoza, Ted R. Miller, Charles Mock, Joseph Murray, Sandra Nolte, In‐Hwan Oh, Bolajoko O. Olusanya   +99 more
openalex   +2 more sources

Pediatric cancer care in Africa: SIOP Global Mapping Program report on economic and population indicators [PDF]

, 2021
Jennifer Geel, Julia Challinor, Neil Ranasinghe, Khumo Hope Myezo, Katherine Eyal, Wuraole Aderounmu, Alan Davidson, Kathy Pritchard‐Jones, Scott C. Howard, Éric Bouffet, Laila Hessissen   +10 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Building global capacity for brain and nervous system disorders research [PDF]

, 2015
Linda B. Cottler, Joseph R. Zunt, Bahr Weiss, Ayeesha Kamran Kamal, Krishna Vaddiparti   +4 more
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Monopolizando el centro. El AKP y el incierto rumbo de la democracia turca

Tiempo Devorado, 2016
La pérdida de impulso reformador y el creciente autoritarismo de la más reciente fase de gobierno del AKP nos indican que la democracia turca está en crisis.
Ziya Öniş
doaj  

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source