Results 121 to 130 of about 5,708,282 (339)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Globalization [PDF]

open access: yesPrehospital and Disaster Medicine, 2006
openaire   +2 more sources

Towards a global psychological science [PDF]

open access: bronze, 2022
J Henrich   +5 more
openalex   +1 more source

Global land use change, economic globalization, and the looming land scarcity

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2011
E. Lambin, P. Meyfroidt
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The challenge to keep global warming below 2 °C

open access: green, 2012
Glen P. Peters   +8 more
openalex   +2 more sources

Interactions between Jumbo Phage SA1 and Staphylococcus: A Global Transcriptomic Analysis [PDF]

open access: gold, 2022
Bingyan Zhang   +4 more
openalex   +1 more source

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