Results 81 to 90 of about 6,311,719 (382)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Utilization of cellulose nanofiber in dental applications: A systematic review of in vitro evidence

open access: yesJapanese Dental Science Review
This systematic review aimed to determine how cellulose nanofiber (CNF) enhance the mechanical properties, biocompatibility, and functional versatility of dental materials, based on in vitro evidence.
Kunhua Yang   +6 more
doaj   +1 more source

Foreign Direct Investment and Productivity: A Cross-Country, Multisector Analysis

open access: yesAsian Development Review, 2019
This paper adopts a cross-country, multisector approach to investigate the intra- and inter-industry effects of foreign direct investment (FDI) on the productivity of 15 emerging market economies in 2000 and 2008.
Rodolphe Desbordes, Loe Franssen
doaj   +1 more source

Global health and global bioethics

open access: yesCadernos Ibero-Americanos de Direito Sanitário, 2021
Covid-19 is not merely a national or regional threat but a global one. It requires coordinated action of the global community. Such action, as argued in this paper, should primarily focus on the question how to prevent the next pandemic. Humankind has been warned multiple time for emerging diseases and the risks of pandemics, although no preparatory ...
openaire   +5 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

The European Refugee Crisis from the Perspective of International Migration Governance

open access: yesJournal of China and International Relations, 2015
The influx of refugees in Europe in 2015 has greatly increased, which not only affects the stability and unity of European society, but also exerts certain pressure on its economic development.
Xie Tingting, Huang Rihan
doaj  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Global Goals and Global Sustainability [PDF]

open access: yesInternational Journal of Environmental Research and Public Health, 2016
On 25 September 2015, the United Nations (UN) member countries adopted an ambitious 17 Sustainable Development Goals (SDGs) aiming to ‘transform the world’ in the next 15 years. [...]
openaire   +3 more sources

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