Results 141 to 150 of about 36,679 (341)

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source

New Parameters for Star Cluster Dynamics: The Role of Clusters’ Initial Conditions

The Astrophysical Journal
We recently introduced three new parameters that describe the shape of the normalized cumulative radial distribution (nCRD) of the innermost stars in globular clusters (GCs) and trace the clusters’ dynamical evolution.
B. Bhat, B. Lanzoni, E. Vesperini, F. R. Ferraro, F. I. Aros, A. Askar, A. Hypki   +6 more
doaj   +1 more source

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh, Ruchi Tanavade, Nik Krajnc, Fabian Föttinger, Theresa König, Martin Krenn, Lukas Haider, Barbara Kornek, Fritz Leutmezer, Kerstin U. Ludwig, Stefan Macher, Tobias Monschein, Markus Ponleitner, Paulus Rommer, Christiane Schmied, Karin Zebenholzer, Tobias Zrzavy, Gudrun Zulehner, Franziska Di Pauli, Axel Schmidt, Harald Hegen, Berthold Pemp, Thomas Berger   +22 more
wiley   +1 more source

The Star Clusters as Links between Galaxy Evolution and Star Formation Project. I. Numerical Method

The Astrophysical Journal
Stellar clusters are critical constituents within galaxies: They are the result of highest-density star formation, and through their spatially and temporally correlated feedback, they regulate their host galaxy evolution.
Marta Reina-Campos, Oleg Y. Gnedin, Alison Sills, Hui Li   +3 more
doaj   +1 more source

Dynamical Evolution of the Mass Function of Globular Star Clusters [PDF]

, 2001
S. Michael Fall, Qing Zhang
openalex   +1 more source

Hot Stars in Globular Clusters

, 1998
26 pages, 11 Postscript figures, to appear in Reviews in Modern Astronomy (Astronomische Gesellschaft)
openaire   +2 more sources

Variable stars in the globular cluster NGC 2419

, 2005
We have used DOLORES at the TNG to obtain B,V time series photometry of NGC 2419, one of the most distant and bright clusters in the Galactic halo. These data will be used to study its variable star population in order to check whether the cluster could be the relic of an extragalactic system accreted by the Milky Way.
Ripepi, V., Greco, C., Baldacci, L., Di Fabrizio, L., Clementini, G., Federici, L., Maio, M., Marconi, M., Musella, I., Stetson, P.   +9 more
openaire   +3 more sources

Single‐Cell RNA Seq in Sydenham Chorea Shows B Cell HLA‐DR/DQ Upregulation and Plasma Cell Proteasomal Activation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han, Brooke A. Keating, Brian S. Gloss, Xianzhong Lau, Ruwani Dissanayake, Hiroya Nishida, Jessica Hayes, Shrujna Patel, Shekeeb S. Mohammad, Russell C. Dale   +9 more
wiley   +1 more source

A New SX Phoenicis Star in the Globular Cluster M15 [PDF]

, 2001
Young‐Beom Jeon, Seung‐Lee Kim, Ho Lee, Myung Gyoon Lee   +3 more
openalex   +1 more source

Moderators and Mediators of Pain and Function Outcomes in a New Service Delivery Model for Management of Knee Osteoarthritis in Primary Care: Secondary Exploratory Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective Our objective was to explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (Optimizing Primary Care Management of Knee Osteoarthritis [PARTNER]), at 12 months (ACTRN: 12617001595303).
Abdolhay Farivar, Jocelyn L. Bowden, Kim L. Bennell, Andrew M. Briggs, Stephen J. Bunker, Rana S. Hinman, Thorlene Egerton, Simon D. French, Marie Pirotta, Karen Schuck, Venkatesha Venkatesha, Nicholas A. Zwar, David J. Hunter   +12 more
wiley   +1 more source