Results 141 to 150 of about 87,149 (376)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Globular Cluster Counts around 700 Nearby Galaxies

open access: yesThe Astrophysical Journal
Empirically, the total number (or total mass) of globular clusters (GCs) bound in a single galactic system correlates with the virial mass of the system. The form of this relation and its intrinsic scatter are potentially valuable constraints on theories
Minh Ngoc Le, Andrew P. Cooper
doaj   +1 more source

Another Faint UV Object Associated with a Globular Cluster X-Ray Source: The Case of M92

open access: yes, 2000
The core of the metal poor Galactic Globular Cluster M92 (NGC 6341) has been observed with WFPC2 on the Hubble Space Telescope through visual, blue and mid-UV filters in a program devoted to study the evolved stellar population in a selected sample of ...
Barbara Paltrinieri   +18 more
core   +1 more source

Globular Clusters and Field Halo Stars [PDF]

open access: yesSymposium - International Astronomical Union, 1988
Recent work on the chemistry and kinematics of the field halo population stars is reviewed, including the metallicity distribution function, elemental abundance patterns, primordial abundances, and their relations with stellar kinematics. The important role played by these stars in determining the ages of the globular clusters is discussed.
openaire   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Binary Stars and Globular Cluster Dynamics [PDF]

open access: yesProceedings of the International Astronomical Union, 2007
AbstractIn this brief proceedings article I summarize the review talk I gave at the IAU 246 meeting in Capri, Italy, glossing over the well-known results from the literature, but paying particular attention to new, previously unpublished material. This new material includes a careful comparison of the apparently contradictory results of two independent
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

An ongoing tidal capture in the Large Magellanic Cloud: the low-mass star cluster KMK88-10 captured by the massive globular cluster NGC 1835? [PDF]

open access: green, 2023
Camilla Giusti   +8 more
openalex   +1 more source

Hot Stars in Globular Clusters

open access: yes, 1998
26 pages, 11 Postscript figures, to appear in Reviews in Modern Astronomy (Astronomische Gesellschaft)
openaire   +2 more sources

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