Results 131 to 140 of about 1,255,310 (311)
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
A Novel Technique for Long-term Timing of Redback Millisecond Pulsars
The Astrophysical JournalWe present timing solutions spanning nearly two decades for five redback (RB) systems found in globular clusters (GCs), created using a novel technique that effectively “isolates” the pulsar. By accurately measuring the time of passage through periastron
Kyle A. Corcoran +8 more
doaj +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
PHANGS Hubble Space Telescope Treasury Survey: Globular Cluster Systems in 17 Nearby Spiral Galaxies
The Astronomical JournalWe present new catalogs of likely globular clusters (GCs) in 17 nearby spiral galaxies studied as part of the PHANGS Hubble Space Telescope (HST) Treasury Survey.
Matthew Floyd +20 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
A new red variable star in the globular cluster M4
, 2004 G302 = L3107 is a red star located at the lowest end of the red giant branch of the globular cluster M4. According to its location on the GM diagram, G302 may be a cluster member.
Sheng, CJ, Lin, Q, Zhang, CS, Yao, BA
core +1 more source
Photometric Analysis of Variable Stars in NGC 6397
The Astronomical JournalThis study investigates a population of low-amplitude, short-period variable stars in the globular cluster NGC 6397, specifically targeting those stars between 11 and 15 mag in the V band.
C.C. Cortés +5 more
doaj +1 more source
On the Theory of Globular Star Clusters [PDF]
Monthly Notices of the Royal Astronomical Society, 1947 openaire +2 more sources