Results 141 to 150 of about 37,443 (293)

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

New Parameters for Star Cluster Dynamics: The Role of Clusters’ Initial Conditions

open access: yesThe Astrophysical Journal
We recently introduced three new parameters that describe the shape of the normalized cumulative radial distribution (nCRD) of the innermost stars in globular clusters (GCs) and trace the clusters’ dynamical evolution.
B. Bhat   +6 more
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

The Local Volume Database: a library of the observed properties of nearby dwarf galaxies and star clusters

open access: yesThe Open Journal of Astrophysics
I present the Local Volume Database (LVDB), a catalog of the observed properties of dwarf galaxies and star clusters in the Local Group and Local Volume.
Andrew B Pace
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

The Star Clusters as Links between Galaxy Evolution and Star Formation Project. I. Numerical Method

open access: yesThe Astrophysical Journal
Stellar clusters are critical constituents within galaxies: They are the result of highest-density star formation, and through their spatially and temporally correlated feedback, they regulate their host galaxy evolution.
Marta Reina-Campos   +3 more
doaj   +1 more source

Helium Mixing in Globular Cluster Stars

open access: yes, 1997
The observed abundance variations in globular cluster red giants indicate that these stars may be mixing helium from the hydrogen shell outward into the envelope, presumably as a result of internal rotation. We have investigated the implications of such helium mixing for both the red- giant-branch (RGB) and horizontal-branch (HB) phases by computing a ...
openaire   +2 more sources

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