Results 111 to 120 of about 2,554 (268)

Star Cluster Evolution: From Young Massive Star Clusters to Old Globulars [PDF]

open access: yes, 2009
Young, massive star clusters are the most notable and significant end products of violent star-forming episodes triggered by galaxy collisions, mergers, and close encounters. The question remains, however, whether or not at least a fraction of the compact YMCs seen in abundance in extragalactic starbursts, are potentially the progenitors of globular ...
openaire   +2 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Spectroscopic Confirmation: Fast Rotators in the Young Clusters NGC 1856 and NGC 1953

open access: yesThe Astrophysical Journal
We present the results of a spectroscopic investigation of two Large Magellanic Cloud globular clusters, NGC 1953 and NGC 1856. Both clusters have similar ages (250 and 300 Myr, respectively). Spectra were recorded with the Michigan/Magellan Fiber System
Paul I. Cristofari   +4 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Cracking the Relation Between Mass and 1P-star Fraction of Globular Clusters. III. Initial Distributions of In Situ and Ex Situ Clusters

open access: yesThe Astrophysical Journal
Galactic globular clusters consist of two main stellar populations, the pristine (1P) and polluted (2P) stars. The fraction of 1P stars in clusters, F _1P , is a decreasing function of the present-day cluster mass, m _prst . The information about cluster
Geneviève Parmentier
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The Local Volume Database: a library of the observed properties of nearby dwarf galaxies and star clusters

open access: yesThe Open Journal of Astrophysics
I present the Local Volume Database (LVDB), a catalog of the observed properties of dwarf galaxies and star clusters in the Local Group and Local Volume.
Andrew B Pace
doaj   +1 more source

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