Results 91 to 100 of about 2,490 (267)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
A Novel Technique for Long-term Timing of Redback Millisecond Pulsars
The Astrophysical JournalWe present timing solutions spanning nearly two decades for five redback (RB) systems found in globular clusters (GCs), created using a novel technique that effectively “isolates” the pulsar. By accurately measuring the time of passage through periastron
Kyle A. Corcoran +8 more
doaj +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
PHANGS Hubble Space Telescope Treasury Survey: Globular Cluster Systems in 17 Nearby Spiral Galaxies
The Astronomical JournalWe present new catalogs of likely globular clusters (GCs) in 17 nearby spiral galaxies studied as part of the PHANGS Hubble Space Telescope (HST) Treasury Survey.
Matthew Floyd +20 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Photometric Analysis of Variable Stars in NGC 6397
The Astronomical JournalThis study investigates a population of low-amplitude, short-period variable stars in the globular cluster NGC 6397, specifically targeting those stars between 11 and 15 mag in the V band.
C.C. Cortés +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Mass Distribution of Binary Black Hole Mergers from Young and Old Dense Star Clusters
The Astrophysical JournalDense star clusters are thought to contribute significantly to the merger rates of stellar-mass binary black holes (BBHs) detected by the LIGO–Virgo–KAGRA collaboration.
Claire S. Ye +3 more
doaj +1 more source