Results 161 to 170 of about 85,801 (378)

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

JWST NIRCam Observations of the Globular Cluster Population of RXJ 2129.7+0005

open access: yesThe Astrophysical Journal
We present an analysis of the globular cluster (GC) population in the galaxy cluster RXJ 2129.7+0005 ( z = 0.234) based on JWST NIRCam imaging in three filters: F115W, F150W, and F200W.
Kaitlyn E. Keatley, William E. Harris
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Retention fractions for globular cluster neutron stars [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1996
To appear in MNRAS, 15 pages, LaTeX, requires MN and epsf styles, includes 3 PS Figures, compressed, uuencoded ...
openaire   +3 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Spectroscopic Study of Globular and Fuzzy Clusters in Lenticular Galaxy NGC 1023

open access: yesThe Astrophysical Journal
We here report the results from spectroscopic observations of a sample of 26 globular cluster (GC) and 21 faint fuzzy (FF) candidates in the lenticular galaxy NGC 1023 using the 10.4 m Gran Telescopio Canarias.
M. A. López-Santamaría   +7 more
doaj   +1 more source

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