Results 161 to 170 of about 334,935 (372)

Binary Stars in Globular and Open Clusters [PDF]

Symposium - International Astronomical Union, 1980
In erecting the edifice we call science, it is given to some to draw the plans by which the entire effort will be guided, to others to lay the foundation stones on which the rest is built, to another group to place the windows that let in light upon the whole, and to still others to cover the result with the paint that will make it acceptable to the ...
openaire   +2 more sources

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Globular Clusters and the Halos of Dwarf Galaxies

Galaxies, 2017
Many dwarf galaxies have disproportionately rich globular cluster (GC) systems for their luminosities. Moreover, the GCs tend to be preferentially associated with the most metal-poor stellar populations in their parent galaxies, making them attractive ...
Søren S. Larsen
doaj   +1 more source

Some Constraints on The Formation of Globular Clusters [PDF]

, 2001
We explore the constraints on globular cluster formation provided by the observed conditions in starbursts where globulars are currently forming, and by the observed properties of young and old globular clusters. We note that the pressure in the ISM of starbursts and mergers implies that molecular clouds in these environments have radii similar to ...
arxiv   +1 more source

The origin of intergalactic thermonuclear supernovae

, 2004
The population synthesis method is used to study the possibility of explaining the appreciable fraction (20^+12_15%) of the intergalactic (no-host) type Ia supernovae observed in galaxy clusters (Gal-Yam ete al.
A. B. Marchant, A. G. Kuranov, A. G. Riess, A. Gal-Yam, B. V. Kukarkin, D. C. Heggie, D. C. Heggie, D. Pooley, E. Capellaro, E. I. Sorokina, E. P. Rubinstein, F. Hoyle, G. Nelemans, I. Iben Jr., J. R. Hurley, J. Whelan, K. A. Postnov, K. Nomoto, L. Spitzer Jr., M. B. Davis, M. Bellazzinni, M. G. Lee, M. M. Shara, N. N. Chugai, N. Trentham, N. V. Dunina-Barkovskaya, R. F. Webbink, R. Napiwotzki, R. W. Michie, S. L. Shapiro, S. Mikkola, S. Perlmutter, S. S. Kim, S. S. Kim, V. M. Lipunov, W. E. Harris, W. Lee   +36 more
core   +2 more sources

Globular cluster star classification: Application to M13 [PDF]

Serbian Astronomical Journal, 2013
Starting from recent determination of Fe, O, Na abundances on a restricted sample (N = 67) of halo and thick disk stars, a natural and well motivated selection criterion is defined for the classification globular cluster stars. An application is performed to M13 using a sample (N = 113) for which Fe, O, Na abundances have been recently ...
openaire   +4 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

A Population of Massive Globular Clusters in NGC 5128

, 2004
We present velocity dispersion measurements of 14 globular clusters in NGC 5128 (Centarus A) obtained with the MIKE echelle spectrograph on the 6.5m Magellan Clay telescope.
Battistini P., Dubath P., Dubath P., Fusi Pecci F., Luis C. Ho, Meylan G., Paul Martini, Rix H., van der Marel R. P.   +8 more
core   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source