Our current understanding of the origins of Homo sapiens is limited, in part, by the fragmented fossil record from Late Pleistocene and early Holocene Africa. Here, we re‐examine the Kabua 1 cranium, an enigmatic and little‐studied Kenyan fossil discovered in the 1950s. We compare virtual reconstructions created previously by our team with a wide range
Abel Marinus Bosman +7 more
wiley +1 more source
High-throughput screening of small-molecules libraries identified antibacterials against clinically relevant multidrug-resistant A. baumannii and K. pneumoniae. [PDF]
Blasco B +25 more
europepmc +1 more source
New Results From the Pre‐Pottery Neolithic Site of Al Uyaynah, Tabuk, in Northwestern Saudi Arabia
ABSTRACT Al Uyaynah is a low sandstone mound on an alluvial plain, long known for its extensive surface remains of stone‐built circular and rectangular structures. Following test excavations in 2012, more detailed excavation was undertaken in 2016 within one of the largest rectangular stone structures.
Khalid Alasmari +6 more
wiley +1 more source
QSTR Models in Dioxins and Dioxin-like Compounds Provide Insights into Gene Expression Dysregulation. [PDF]
Eleazar EG +4 more
europepmc +1 more source
Between the Indian Ocean and the Gulf: Ceramics From Ḥattā Oasis in the Emirate of Dubai
ABSTRACT This study presents the ceramic finds from archaeological investigations conducted in 2024 at two settlements: ‘Islamic Village' and Suhaila 2, one of a number of mountain villages of the Late Islamic period within the Ḥattā Oasis: a high‐altitude exclave in the Emirate of Dubai. The sites are located on the northeastern slopes of Jabal Qallāt
Seth M. N. Priestman +3 more
wiley +1 more source
Context-dependent cytotoxicity and ADMET profiling of methoxylated flavonoids as novel leads for metastatic prostate cancer. [PDF]
Hourani W.
europepmc +1 more source
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza +16 more
wiley +1 more source
Guiding the Way: Traditional Medicinal Chemistry Inspiration for Rational Gram-Negative Drug Design. [PDF]
Stoorza AM, Duerfeldt AS.
europepmc +1 more source
Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane +12 more
wiley +1 more source
Target Mapping in Cancer: Ligandable Protein Pockets on 3D OncoPPI Networks. [PDF]
Trisciuzzi D +4 more
europepmc +1 more source

