Results 1 to 10 of about 690,492 (301)

Isolation, Purification and Crystallization of Restriction Enzyme Bsa I and Its Preparation of Seleno-derived Derivatives

open access: yesShipin gongye ke-ji, 2023
Objective: To screen and optimize the method for preparing three-dimensional structural samples of restriction endonuclease Bsa I. Methods: In this study, the Escherichia coli expression system was employed to express the Bsa I protein and its ...
Hai ZHU   +8 more
doaj   +1 more source

VHL-HIF-2α axis-induced SEMA6A upregulation stabilized β-catenin to drive clear cell renal cell carcinoma progression

open access: yesCell Death and Disease, 2023
SEMA6A is a multifunctional transmembrane semaphorin protein that participates in various cellular processes, including axon guidance, cell migration, and cancer progression.
Jing Ji   +23 more
doaj   +1 more source

Surface Functionalized Magnetic Nanoparticles as a Selective Sorbent for Affinity Fishing of PPAR-γ Ligands from Choerospondias axillaris

open access: yesMolecules, 2022
Coronary heart disease (CHD), which has developed into one of the major diseases, was reported to be treated by the target of peroxisome proliferators-activate receptor γ (PPAR-γ).
Miaomiao Chi   +5 more
doaj   +1 more source

FBXO2 targets glycosylated SUN2 for ubiquitination and degradation to promote ovarian cancer development

open access: yesCell Death and Disease, 2022
SAD1/UNC84 domain protein-2 (SUN2) plays a tumor suppressor role in various types of cancer by inhibiting cancer cell proliferation, migration and promoting apoptosis.
Jing Ji   +10 more
doaj   +1 more source

Synergistic Antinociceptive Effects of Indomethacin–Pregabalin and Meloxicam–Pregabalin in Paclitaxel-Induced Neuropathic Pain

open access: yesBiomedicines, 2022
Neuropathic pain is often closely associated with nerve injury or inflammation, and the role of traditional nonsteroidal anti-inflammatory drugs as adjuvants for treating chemotherapy-induced peripheral neuropathic pain remains unclear.
Yurong Ma   +6 more
doaj   +1 more source

Microwave-Assisted Extraction Coupled with Mass Spectrometry for Determining Five Volatile Compounds from Soy Sauces

open access: yesJournal of Analytical Methods in Chemistry, 2021
As a popular fermented condiment in oriental countries, soy sauce plays a more and more important role in modern food culture due to its unique smell and delicious taste.
Kai Xu   +8 more
doaj   +1 more source

Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Aeromonas sobria, a common conditional pathogenic bacteria, is widely distributed in the environment and causes gastroenteritis in humans or septicemia in fish. Of all Aeromonas species, A.
Wei Zhang   +9 more
doaj   +1 more source

One-factor-at-a-time method combined with ICP-MS for determining 11 elements in soy sauce and their migration from the containing glass bottles

open access: yesReviews in Analytical Chemistry, 2021
This study was designed to determine the 11 metal elements (Al, Cr, Mn, Fe, As, Ni, Cu, Zn, Cd, Sb, and Pb) in soy sauce and their migration from the containing glass bottles.
Gao Xun   +3 more
doaj   +1 more source

Isolation and Characterization of an Unknown Process-Related Impurity in Furosemide and Validation of a New HPLC Method

open access: yesMolecules, 2023
Furosemide is a widely used loop diuretic in the treatment of congestive heart failure and edema. During the preparation of furosemide, a new process-related impurity G in the levels ranging from 0.08% to 0.13% was detected in pilot batches by a new high
Ao Xu   +9 more
doaj   +1 more source

Determination of four parabens in cosmetics by high-performance liquid chromatography with magnetic solid-phase and ionic dispersive liquid–liquid extraction

open access: yesReviews in Analytical Chemistry, 2021
To determine the trace amount of four benzoic acid esters in cosmetics, ionic dispersive liquid–liquid microextraction (DLLME) and magnetic solid-phase extraction were combined and optimized.
Gao Xun   +7 more
doaj   +1 more source

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