Results 41 to 50 of about 359,557 (359)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

A Rapid and Sensitive Detection Method for Pseudomonas aeruginosa Using Visualized Recombinase Polymerase Amplification and Lateral Flow Strip Technology

Frontiers in Cellular and Infection Microbiology, 2021
Pseudomonas aeruginosa is a common opportunistic pathogen that causes acute nosocomial necrotizing pneumonia and is the predominant source of chronic lung infections in patients with the genetic disorder cystic fibrosis.
Haitao Yang, Yan Wang, Qiankun Yang, Hui Fan, Lei Wang, Lei Wang, Tianmeng Zhang, Zhixing Li, Gang Liu, Panpan Zhao, Panpan Zhao, Huahua Wu, Jingquan Dong, Wei Liang   +13 more
doaj   +1 more source

A high-throughput screening of a chemical compound library in ovarian cancer stem cells [PDF]

, 2018
This work was performed under the frame of COST Action collaboration (COST Action CM1106). The generous contribution of AIRC (The Italian Association for Cancer Research) IG14536 to G.D. is gratefully acknowledged. A.H.
Botta, B., Bősze, Szilvia, S. Dallavalle, Benhida, B., Christodoulou, M S, Benhida, R, B. Kaminska, N. Martinet, Westwood, N., Musso, L, Athanassopulos, C. M., Michel, B., Hansen, T. V., Bősze, S., C. M. Athanassopoulos, Christodoulou, M. S., Dallavalle , S., Hansen, T V, Martinet, N, Athanassopoulos, C. M., Silvestri, R, Botta, B, Hunyadi, A., F. Ricci, Majer, Z., Mori, M., Dallavalle, S, C. Ingallina, A. Hunyadi, M. Mori, Roussis, V, A. Detsi, Martinet , N., Passarella, D., Hunyadi, A, Bertrand, P, Athanassopoulos, C M, F. Hudecz, Carrassa, L., E. Ioannou, Carrassa, L, Kaminska, B., M. S. Christodoulou, D. Passarella, Kavetsou, E., G. Damia, P. Bertrand, Detsi, A, E. Kavetsou, Ingallina, C, B. Botta, Majer, Z, B. Michel, R. Silvestri, Musso, L., Silvestri, R., Roussis, V., Damia, G, R. Benhida, L. Musso, Kaminska, B, Christodoulou, M., Hudecz, F, Ioannou, E, Bertrand, P., V. Roussis, Dallavalle, S., Z. Majer, Damia, G., N. Westwood, Kavetsou, E, Mori, M, Ricci, F, Ioannou, E., Bertrand, Pierre, Ingallina, C., Bosze, S, T.V. Hansen, Westwood, Nicholas James, Westwood, N, Hansen, V., Athanassopoulos, M., L. Carrassa, Michel, B, Ricci, F., Hudecz, F., Benhida, R., Martinet, N., Hudecz, Ferenc, Detsi, A., Passarella, D, S. Bosze   +91 more
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Rapid Detection of Enterocytozoon hepatopenaei Infection in Shrimp With a Real-Time Isothermal Recombinase Polymerase Amplification Assay

Frontiers in Cellular and Infection Microbiology, 2021
Enterocytozoon hepatopenaei (EHP) infection has become a significant threat in shrimp farming industry in recent years, causing major economic losses in Asian countries.
Chao Ma, Shihui Fan, Yu Wang, Haitao Yang, Yi Qiao, Ge Jiang, Mingsheng Lyu, Jingquan Dong, Hui Shen, Song Gao   +9 more
doaj   +1 more source

Statistical Analysis of High Content Screening Data [PDF]

, 2009
High throughput screening experiments are typically used within the pharmaceutical industry for the identification and evaluation of candidate drugs. Using a high throughput screen with automated imaging platform allows a large number of compounds to be ...
Jacques, Richard
core  

Plate-based diversity subset screening generation 2: An improved paradigm for high throughput screening of large compound files [PDF]

, 2016
High throughput screening (HTS) is an effective method for lead and probe discovery that is widely used in industry and academia to identify novel chemical matter and to initiate the drug discovery process.
Hongyao Zhu, Sharp, Robert E., Everett, Jeremy, James Mills, Peakman, Marie-Claire, Sharp, Robert E, Marie-Claire Peakman, Joseph Bradley, Bradley, Joseph, Bell, Andrew S., Mills, James, Williams, Christine, Zhu, Hongyao, Jeremy R. Everett, David McLoughlin, McLoughlin, David, Everett, Jeremy R, Bell, Andrew S, Pfizer Worldwide Research & Development, Robert E. Sharp, Andrew S. Bell, Loesel, Jens, Christine Williams, Jens Loesel   +23 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Difenoconazole causes spleen tissue damage and immune dysfunction of carp through oxidative stress and apoptosis

Ecotoxicology and Environmental Safety, 2022
As the use of pesticides increases year after year, so does the level of residual pesticides in the aquatic environment, posing a serious threat to non-target organisms.
Feixue Liu, Xueqing Li, Babatunde Kazeem Bello, Tianmeng Zhang, Haitao Yang, Kun Wang, Jingquan Dong   +6 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source