Results 211 to 220 of about 1,212 (266)

Graphene oxide–modified fluoridated varnish promotes mineral recovery in demineralized bovine enamel: An in vitro study

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract This in vitro study evaluated the efficacy of an experimental fluoridated varnish modified with graphene oxide (GO) nanoparticles in arresting initial caries lesion progression and promoting mineral recovery in demineralized bovine enamel.
Mariana Souza Rodrigues   +5 more
wiley   +1 more source

The Quantification of Drug Accumulation within Gram-Negative Bacteria. [PDF]

open access: yesACS Infect Dis
George A   +8 more
europepmc   +1 more source

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

open access: yesThe FEBS Journal, EarlyView.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam   +4 more
wiley   +1 more source

The epigenetic landscape of skeletal muscle in response to exercise and aging

open access: yesThe FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

Phenotypic characterization of Arabidopsis thaliana mutants that alleviate root growth defects in a vitamin B6 biosynthesis mutant

open access: yesThe FEBS Journal, EarlyView.
Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra   +4 more
wiley   +1 more source

Target Mapping in Cancer: Ligandable Protein Pockets on 3D OncoPPI Networks. [PDF]

open access: yesPharmaceuticals (Basel)
Trisciuzzi D   +4 more
europepmc   +1 more source

Molecular dynamics simulations elucidate the misfolding mechanisms of secretion‐defective pancreatic lipase variants

open access: yesThe FEBS Journal, EarlyView.
Misfolding mutations in pancreatic lipase have been identified as potential contributors of chronic pancreatitis, an inflammatory disease of the human pancreas. Here, we describe the effect of these misfolding mutations on pancreatic lipase structure using molecular dynamics simulations and structural modeling.
Gyula Hoffka, András Szabó
wiley   +1 more source

A chemo‐enzymatic colorimetric cascade for detecting ethylene glycol contamination

open access: yesThe FEBS Journal, EarlyView.
A chemo‐enzymatic cascade is developed for ethylene glycol (EG) detection. EG is oxidized by GoADH with C1‐mediated cofactor recycling to produce glycolaldehyde (GAL). GAL subsequently reacts with purpald to generate a detectable purple chromophore.
Tawatchai Singphongam   +6 more
wiley   +1 more source

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