Results 91 to 100 of about 52,751 (312)

Automated segmentation of cerebral deep gray matter from MRI scans: effect of field strength on sensitivity and reliability

BMC Neurology, 2017
Background The cerebral subcortical deep gray matter nuclei (DGM) are a common, early, and clinically-relevant site of atrophy in multiple sclerosis (MS).
Renxin Chu, Shelley Hurwitz, Shahamat Tauhid, Rohit Bakshi   +3 more
doaj   +1 more source

Incidence Rate and Predictors of Globus Pallidus Necrosis after Charcoal Burning Suicide [PDF]

, 2019
Objective: This study examined predictors of globus pallidus necrosis as there was a paucity of literature of globus pallidus necrosis resulted from carbon monoxide poisoning after charcoal burning suicide.
Chen, Yu-Chin, Hong, Hsiang-Hsi, Hou, Yi-Chou, Hsu, Ching-Wei, Huang, Wen-Hung, Ku, Chung-Hsuan, Wang, I-Kuan, Wang, Yen-Li, Weng, Cheng-Hao, Yen, Tzung-Hai   +9 more
core   +1 more source

Clinical and Imaging Correlates of Medication Reduction in Globus Pallidus Stimulation for Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The magnitude and factors associated with levodopa equivalent daily dose (LEDD) reduction in deep brain stimulation (DBS) of the globus pallidus interna (GPi) for Parkinson's Disease (PD) remain unclear. Objective To investigate LEDD reduction in GPi DBS and its correlation with anatomical/clinical characteristics.
Daniel G. Di Luca, Carolina Ramirez‐Gomez, Brendan Santyr, Marco Fumagalli, Jürgen Germann, Suneil K. Kalia, Andres M. Lozano, Alfonso Fasano   +7 more
wiley   +1 more source

Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano, Carolina Gorodetsky, Darcia Paul, Jürgen Germann, Aaron Loh, Han Yan, Peter L. Carlen, Sara Breitbart, Andres M. Lozano, George M. Ibrahim, Suneil K. Kalia   +10 more
wiley   +1 more source

Changes in the globus pallidus in chronic kernicterus

Journal of Pediatric Neurosciences, 2009
The objective of the study was to establish the diagnosis of kernicterus as a cause of seizures and abnormal movements in a 1-year-old child. We performed an MRI of the brain of the child on our 1.5 T scanner. The MRI of the patient showed high signals on T2-weighted images in the globus pallidus bilaterally, with no evidence of mass effect. Because of
Rajesh Yadav, Pallavi Aga, Umesh C Parashari, Ragini Raj Singh   +3 more
openaire   +3 more sources

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange, Naomi I. Kremer, Teus van Laar, Fiete Lange, T. Elien Steendam‐Oldekamp, D. L. Marinus Oterdoom, Anthony R. Absalom, J. Marc C. van Dijk, Gea Drost   +8 more
wiley   +1 more source

A hierarchical coding-window model of Parkinson's disease [PDF]

arXiv, 2013
Parkinson's disease is an ongoing challenge to theoretical neuroscience and to medical treatment. During the evolution of the disease, neurodegeneration leads to physiological and anatomical changes that affect the neuronal discharge of the Basal Ganglia to an extent that impairs normal behavioral patterns.
arxiv  

Empirical comparison of diffusion kurtosis imaging and diffusion basis spectrum imaging using the same acquisition in healthy young adults [PDF]

, 2017
As diffusion tensor imaging gains widespread use, many researchers have been motivated to go beyond the tensor model and fit more complex diffusion models, to gain a more complete description of white matter microstructure and associated pathology.
Grabowski, Thomas J, Li, Wenbin, Madhyastha, Tara M, Peterson, Daniel J, Wang, Qing, Wang, Sijia, Wang, Yong   +6 more
core   +2 more sources

Long-term follow-up of DYT1 dystonia patients treated by deep brain stimulation: an open-label study [PDF]

Mov Disord. 2010 Feb 15;25(3):289-99
Long-term efficacy of internal globus pallidus (GPi) deep-brain stimulation (DBS) in DYT1 dystonia and disease progression under DBS was studied. Twenty-six patients of this open-label study were divided into two groups: (A) with single bilateral GPi lead, (B) with a second bilateral GPi lead implanted owning to subsequent worsening of symptomatology ...
arxiv   +1 more source

Cholinergic Stimulation of Globus Pallidus in Man.

Experimental Biology and Medicine, 1959
SummaryA 10% solution of acetylcholine chloride injected into the globus pallidus of persons with Parkinsonism resulted in initial excitatory stage with increase in tremor and parasympathetic activation. Parasympathetic response was blocked by intracerebral injection of an anticholinergic drug, oxyphenonium bromide.
openaire   +3 more sources