Results 101 to 110 of about 56,426 (309)
Striatal activity is associated with deficits of cognitive control and aberrant salience for patients with schizophrenia [PDF]
, 2016 A recent meta-analysis has shown that a large dopamine abnormality exists in the striatum when comparing patients with schizophrenia and controls, and this abnormality is thought to contribute to aberrant salience assignment (or a misattribution of ...
Barch, Deanna M, Ceaser, Alan E
core +2 more sources
Movement Disorders Clinical Practice, EarlyView.Abstract Background Anticholinergic medications and botulinum neurotoxin injections are established treatments for dystonia, yet they carry potential side effects and practical challenges. Deep brain stimulation (DBS) is offered in case of poor response to these approaches.
Marcela A. Montiel +5 more
wiley +1 more source
Arquivos de Neuro-Psiquiatria, 1994 Thalamic ventrobasal (VB) stimulation, first performed by Mazars, in 1961, is a valuable means for treating central and deafferentation pain. The way it acts to achieve pain relief, however, is still a matter of controversy.
Osvaldo Vilela Filho
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Deep brain stimulation (DBS) is effective for Parkinson's disease (PD); however, its efficacy varies with genetic background, such as the GBA1 variant—the causative gene of Gaucher disease—associated with increased PD risk and cognitive decline after subthalamic nucleus (STN)‐DBS.
Hikaru Kamo +14 more
wiley +1 more source
Annals of Indian Academy of Neurology, 2020 Succinic semialdehyde dehydrogenase (SSADH) deficiency is an autosomal recessive disorder of gamma-aminobutyric acid metabolism. Children with SSADH deficiency usually manifest with developmental delay, behavioral symptoms, language dysfunction, seizures,
Sangeetha Yoganathan +7 more
doaj +1 more source
Structural brain change in Attention Deficit Hyperactivity Disorder identified by meta-analysis. [PDF]
, 2011 BACKGROUND: The authors sought to map gray matter changes in Attention Deficit Hyperactivity Disorder (ADHD) using a novel technique incorporating neuro-imaging and genetic meta-analysis methods. METHODS: A systematic search was conducted for voxel-based
Bullmore, Ed +2 more
core +1 more source
Dystonia Scales for Children: Challenges and Obstacles in DBS Practice
Movement Disorders Clinical Practice, EarlyView.Abstract Background Dystonia in pediatric patients often coexists with other movement disorders and neurodevelopmental issues. Current rating scales for evaluating pediatric deep brain stimulation (DBS) candidates are not universally applicable and often require a non‐validated combination of the existing scales.
Marcela Montiel +4 more
wiley +1 more source
Surgical Treatment of Tremor Syndromes: A Guide to the Clinician
Movement Disorders Clinical Practice, EarlyView.Abstract Background Tremor is a common feature of multiple neurological conditions, and while medications can be effective in mild cases, surgical interventions are often required in moderate–severe syndromes or when medication side‐effects are unacceptable.
James Peters +5 more
wiley +1 more source
Neurobiology of Disease, 2005 This study investigated the consequences of levodopa treatment on the expression of the 65- and 67-kDa isoforms of glutamate decarboxylase (GAD65 and GAD67) immunoreactivity in the basal ganglia and cortex of monkeys rendered Parkinsonian by systemic ...
Diane T. Stephenson +6 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Bilateral globus pallidus internus deep brain stimulation (GPi‐DBS) is a proven safe and effective treatment in certain forms of idiopathic or inherited dystonia (ID/IN). Its effects in acquired dystonia such as in dyskinetic cerebral palsy (DCP) however vary widely.
Katerina Bernardi +16 more
wiley +1 more source