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[Deep Brain Stimulation of Globus Pallidus]. [PDF]
The globus pallidus internus(GPi)has evolved as a potential target for deep brain stimulation(DBS)in patients with advanced Parkinson's disease(PD). GPi stimulation has a significant impact on intractable hyperkinetic movement disorders. Optimal surgical procedures require a combination of image-based targeting and intraoperative microelectrode ...
Masaki Izumi+3 more
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Synaptic organization of the globus pallidus
Journal of Electron Microscopy Technique, 1988AbstractThe synaptic organization of the globus pallidus is reviewed with respect to present knowledge about neurons, fibers, axon terminals, and their intrinsic synaptic relationships. Information derived from studies employing Nissl stains, Golgi impregnations, lesion degeneration techniques, immunohistochemistry, and anterograde axonal labeling in ...
José A. Rafols, Marian DiFiglia
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Projections of the feline globus pallidus
Brain Research, 1980The organization of globus pallidus (GP) projections was studied in cats using autoradiographic and horseradish peroxidase (HRP) techniques. Both methods confirmed the existence of a topographically organized projection to subthalamic nucleus (STN).
Kenneth D. Larsen, Russell L. McBride
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The radial fibers in the globus pallidus
Journal of Comparative Neurology, 1975AbstractIn our Golgi collection of adult monkey brains the striatal efferents, i.e., the radial fibers in the globus pallidus and the “comb” bundle fibers in the internal capsule and in the cerebral peduncle, are well impregnated in the horizontally sectioned brain and in a sagittal sectioned brain.
Clement A. Fox, José A. Rafols
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The control of amygdaloid seizures by the globus pallidus
Experientia, 1981Both in acute and chronic cats entopeduncular stimulation inhibits, to a greater extent than caudate activation, focal paroxysmal activity in the ventro-basal complex of the amygdala. Lesion of entopeduncular neurons, by means of kainic acid injection, induces a decrease of the caudate inhibitory effect.
V. La Grutta+3 more
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Electrophysiology of globus pallidus neurons in vitro
Journal of Neurophysiology, 19941. We investigated the electrical properties of globus pallidus neurons intracellularly using brain slices from adult guinea pigs. Three types of neurons were identified according to their intrinsic electrophysiological properties. 2. Type I neurons (59%) were silent at the resting membrane level (-65 +/- 10 mV, mean +/- SD) and generated a burst of ...
Atsushi Nambu, Rodolfo R. Llinás
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Role of the globus pallidus in the mechanisms of memory
Neuroscience and Behavioral Physiology, 19831. Animals with bilateral incomplete lesions of the globus pallidus “forget” previous electric shock punishment and in the same experimental situation behave as if they had not been shocked before. 2. Bilateral incomplete destruction of the globus pallidus disturbs the “remembering” of the sequence of alternation of food conditioned ...
L. S. Gambaryan, Zh. S. Sarkisyan
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A Golgi study on the globus pallidus of the mouse
Journal of Comparative Neurology, 1981AbstractThe globus pallidus (GP) of the mouse was studied by the rapid Golgi silver impregnation method. The GP was composed of large and mediumsized neurons. The large neurons had stellate cell bodies with a mean diameter of 25 μm by 28 μm and five to seven primary dendrites.
Noboru Mizuno, Nobuharu Iwahori
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Globus pallidus external segment
2007The external segment of the pallidum (GP(e)) is a relatively large nucleus located caudomedial to the neostriatum (Str). The GP(e) receives major inputs from two major basal ganglia input nuclei, the Str and the subthalamic nucleus (STN), and sends its output to many basal ganglia nuclei including the STN, the Str, the internal pallidal segment (GP(i)),
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Stimulation of the globus pallidus in Parkinson's disease
British Journal of Neurosurgery, 1995In 62 patients undergoing posteroventral pallidotomy (PVP) for the treatment of Parkinson's disease, we have demonstrated significant (p < 0.01) elimination of akinetic features and other symptoms during intraoperative stimulation trials in areas anterior to the PVP target (n = 30).
Sh. Yamada+3 more
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