Mean-field modeling of the basal ganglia-thalamocortical system. I. Firing rates in healthy and parkinsonian states [PDF]
Parkinsonism leads to various electrophysiological changes in the basal ganglia-thalamocortical system (BGTCS), often including elevated discharge rates of the subthalamic nucleus (STN) and the output nuclei, and reduced activity of the globus pallidus external segment (GPe).
arxiv +1 more source
Neural correlates of enhanced visual short-term memory for angry faces: An fMRI study [PDF]
Copyright: © 2008 Jackson et al.Background: Fluid and effective social communication requires that both face identity and emotional expression information are encoded and maintained in visual short-term memory (VSTM) to enable a coherent, ongoing picture
AA Utter+62 more
core +9 more sources
Correlation between relaxometry and diffusion tensor imaging in the globus pallidus of Huntington's disease patients. [PDF]
Huntington's disease (HD) is an inherited neurodegenerative disorder with progressive impairment of motor, behavioral and cognitive functions. The clinical features of HD are closely related to the degeneration of the basal ganglia, predominantly the ...
Michael Syka+7 more
doaj +1 more source
The external pallidum: think locally, act globally [PDF]
The globus pallidus (GPe) of the basal ganglia has been underappreciated for decades due to poor understanding of its cells and circuits. The advent of molecular tools has sparked a resurgence in interest in the GPe. Here, we review a recent flurry of publications that has unveiled the complexity of the molecular landscape and cellular composition ...
arxiv
A longitudinal study of patients with cirrhosis treated with L-ornithine L-aspartate, examined with magnetization transfer, diffusion-weighted imaging and magnetic resonance spectroscopy [PDF]
The presence of overt hepatic encephalopathy (HE) is associated with structural, metabolic and functional changes in the brain discernible by use of a variety of magnetic resonance (MR) techniques.
Bak-Bol, A+14 more
core +2 more sources
GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming
Levo-dihydroxyphenylalanine (L-DOPA) is the most effective treatment for Parkinson's disease; however, most patients develop uncontrollable abnormal involuntary movements known as L-DOPA-induced dyskinesia.
Haruo Nishijima+10 more
doaj
Sex Commonalities and Differences in Obesity-Related Alterations in Intrinsic Brain Activity and Connectivity. [PDF]
OBJECTIVE:This study aimed to characterize obesity-related sex differences in the intrinsic activity and connectivity of the brain's reward networks. METHODS:Eighty-six women (n = 43) and men (n = 43) completed a 10-minute resting functional magnetic ...
Anderberg+44 more
core +1 more source
Microstructural changes within the basal ganglia differ between Parkinson disease subtypes
Diffusion tensor imaging (DTI) of the substantia nigra has shown promise in detecting and quantifying neurodegeneration in Parkinson disease (PD). It remains unknown, however, whether differences in microstructural changes within the basal ganglia ...
Lidia M Nagae+6 more
doaj +1 more source
ObjectivesBrain iron deposition and microstructural changes in brain tissue are associated with Parkinson’s disease (PD). However, the correlation between these factors in Parkinson’s disease has been little studied.
Lin Yang+12 more
doaj +1 more source
Gadolinium deposition in the brain: Another concern regarding gadolinium-based contrast agents [PDF]
Not ...
Karabulut, Nevzat
core +2 more sources