Results 41 to 50 of about 52,751 (312)

Mean-field modeling of the basal ganglia-thalamocortical system. I. Firing rates in healthy and parkinsonian states [PDF]

open access: yesJ. Theor. Biol. 257: 642-663 (2009), 2018
Parkinsonism leads to various electrophysiological changes in the basal ganglia-thalamocortical system (BGTCS), often including elevated discharge rates of the subthalamic nucleus (STN) and the output nuclei, and reduced activity of the globus pallidus external segment (GPe).
arxiv   +1 more source

Neural correlates of enhanced visual short-term memory for angry faces: An fMRI study [PDF]

open access: yes, 2008
Copyright: © 2008 Jackson et al.Background: Fluid and effective social communication requires that both face identity and emotional expression information are encoded and maintained in visual short-term memory (VSTM) to enable a coherent, ongoing picture
AA Utter   +62 more
core   +9 more sources

Correlation between relaxometry and diffusion tensor imaging in the globus pallidus of Huntington's disease patients. [PDF]

open access: yesPLoS ONE, 2015
Huntington's disease (HD) is an inherited neurodegenerative disorder with progressive impairment of motor, behavioral and cognitive functions. The clinical features of HD are closely related to the degeneration of the basal ganglia, predominantly the ...
Michael Syka   +7 more
doaj   +1 more source

The external pallidum: think locally, act globally [PDF]

open access: yesarXiv, 2021
The globus pallidus (GPe) of the basal ganglia has been underappreciated for decades due to poor understanding of its cells and circuits. The advent of molecular tools has sparked a resurgence in interest in the GPe. Here, we review a recent flurry of publications that has unveiled the complexity of the molecular landscape and cellular composition ...
arxiv  

A longitudinal study of patients with cirrhosis treated with L-ornithine L-aspartate, examined with magnetization transfer, diffusion-weighted imaging and magnetic resonance spectroscopy [PDF]

open access: yes, 2016
The presence of overt hepatic encephalopathy (HE) is associated with structural, metabolic and functional changes in the brain discernible by use of a variety of magnetic resonance (MR) techniques.
Bak-Bol, A   +14 more
core   +2 more sources

GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming

open access: yesNeurobiology of Disease, 2020
Levo-dihydroxyphenylalanine (L-DOPA) is the most effective treatment for Parkinson's disease; however, most patients develop uncontrollable abnormal involuntary movements known as L-DOPA-induced dyskinesia.
Haruo Nishijima   +10 more
doaj  

Sex Commonalities and Differences in Obesity-Related Alterations in Intrinsic Brain Activity and Connectivity. [PDF]

open access: yes, 2018
OBJECTIVE:This study aimed to characterize obesity-related sex differences in the intrinsic activity and connectivity of the brain's reward networks. METHODS:Eighty-six women (n = 43) and men (n = 43) completed a 10-minute resting functional magnetic ...
Anderberg   +44 more
core   +1 more source

Microstructural changes within the basal ganglia differ between Parkinson disease subtypes

open access: yesFrontiers in Neuroanatomy, 2016
Diffusion tensor imaging (DTI) of the substantia nigra has shown promise in detecting and quantifying neurodegeneration in Parkinson disease (PD). It remains unknown, however, whether differences in microstructural changes within the basal ganglia ...
Lidia M Nagae   +6 more
doaj   +1 more source

Combined Application of Quantitative Susceptibility Mapping and Diffusion Kurtosis Imaging Techniques to Investigate the Effect of Iron Deposition on Microstructural Changes in the Brain in Parkinson’s Disease

open access: yesFrontiers in Aging Neuroscience, 2022
ObjectivesBrain iron deposition and microstructural changes in brain tissue are associated with Parkinson’s disease (PD). However, the correlation between these factors in Parkinson’s disease has been little studied.
Lin Yang   +12 more
doaj   +1 more source

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