Results 41 to 50 of about 56,426 (309)
Chaotic desynchronization as the therapeutic mechanism of deep brain stimulation
Frontiers in Systems Neuroscience, 2011 High frequency deep-brain stimulation of the subthalamic nucleus (DBS) relieves many of the symptoms of Parkinson's disease in humans and animal models. Although the treatment has seen widespread use, its therapeutic mechanism remains paradoxical. The
Charles J Wilson +2 more
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The role of the left head of caudate in suppressing irrelevant words [PDF]
, 2009 Suppressing irrelevant words is essential to successful speech production and is expected to involve general control mechanisms that reduce interference from task-unrelated processing.
Ali, N. +4 more
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Diagnostic value of conventional MRI combined with DTI for neonatal hyperbilirubinemia
Pediatrics and Neonatology, 2018 Background: Neonatal hyperbilirubinemia (NHB) is a common clinical disease and can cause bilirubin encephalopathy in severe cases. It is now widely accepted that increased signal intensity in the globus pallidus on MR T1WI is an important sign of ...
Ruifang Yan +5 more
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Correlation between relaxometry and diffusion tensor imaging in the globus pallidus of Huntington's disease patients. [PDF]
PLoS ONE, 2015 Huntington's disease (HD) is an inherited neurodegenerative disorder with progressive impairment of motor, behavioral and cognitive functions. The clinical features of HD are closely related to the degeneration of the basal ganglia, predominantly the ...
Michael Syka +7 more
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Dichotomous Organization of the External Globus Pallidus [PDF]
Neuron, 2012 Different striatal projection neurons are the origin of a dual organization essential for basal ganglia function. We have defined an analogous division of labor in the external globus pallidus (GPe) of Parkinsonian rats, showing that the distinct temporal activities of two populations of GPe neuron in vivo are underpinned by distinct molecular profiles
Mallet, Nicolas +7 more
openaire +5 more sources
Microstructural changes within the basal ganglia differ between Parkinson disease subtypes
Frontiers in Neuroanatomy, 2016 Diffusion tensor imaging (DTI) of the substantia nigra has shown promise in detecting and quantifying neurodegeneration in Parkinson disease (PD). It remains unknown, however, whether differences in microstructural changes within the basal ganglia ...
Lidia M Nagae +6 more
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Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types. [PDF]
, 2017 Many subtypes of cortical interneurons (CINs) are found in adult mouse cortices, but the mechanism generating their diversity remains elusive. We performed single-cell RNA sequencing on the mouse embryonic medial ganglionic eminence (MGE), the major ...
Chen, Ying-Jiun J +7 more
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Frontiers in Cellular Neuroscience, 2010 The globus pallidus plays a central integrative role in the basal ganglia circuitry. Morphological studies have revealed a high level of GABA and GABAA receptors in the globus pallidus.
Yan Xue, Xiao-Hua Han, Lei Chen
doaj +1 more source
Frontiers in Aging Neuroscience, 2022 ObjectivesBrain iron deposition and microstructural changes in brain tissue are associated with Parkinson’s disease (PD). However, the correlation between these factors in Parkinson’s disease has been little studied.
Lin Yang +12 more
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Empirical comparison of diffusion kurtosis imaging and diffusion basis spectrum imaging using the same acquisition in healthy young adults [PDF]
, 2017 As diffusion tensor imaging gains widespread use, many researchers have been motivated to go beyond the tensor model and fit more complex diffusion models, to gain a more complete description of white matter microstructure and associated pathology.
Grabowski, Thomas J +6 more
core +2 more sources