Results 51 to 60 of about 52,751 (312)

Effects of pharmacological block of GABAA receptors on pallidal neurons in normal and parkinsonian state

Frontiers in Cellular Neuroscience, 2010
The globus pallidus plays a central integrative role in the basal ganglia circuitry. Morphological studies have revealed a high level of GABA and GABAA receptors in the globus pallidus.
Yan Xue, Xiao-Hua Han, Lei Chen
doaj   +1 more source

The external globus pallidus: progress and perspectives [PDF]

European Journal of Neuroscience, 2016
AbstractThe external globus pallidus (GPe) of the basal ganglia is in a unique and powerful position to influence processing of motor information by virtue of its widespread projections to all basal ganglia nuclei. Despite the clinical importance of theGPe in common motor disorders such as Parkinson's disease, there is only limited information about ...
C. Savio Chan, Ellie S. Hong, Vivian M. Hernández, Daniel J. Hegeman   +3 more
openaire   +3 more sources

Neuronal entropy depends on the level of alertness in the parkinsonian globus pallidus in vivo [PDF]

, 2014
A new working hypothesis of Parkinson's disease (PD) proposes to focus on the central role of entropy increase in the basal ganglia (BG) in movement disorders. The conditions necessary for entropy increase in vivo are, however, still not fully described.
Andres, Daniela Sabrina, Cerquetti, Daniel, Merello, Marcelo Jorge, Stoop, Ruedi   +3 more
core   +3 more sources

Persistent disturbance of consciousness with bilateral globus pallidus and substantia nigra lesions in 2 patients with severe COVID-19 pneumonia

Radiology Case Reports, 2022
With an increasing number of cases of Coronavirus disease 2019 (COVID-19), various neurological complications have been reported; however, some of these have not been fully elucidated.
Takayuki Kurinobu, MD, Junko Araki, MD, PhD, Kumi Kamoshida, MD, Yasuhiro Kunihiro, MD, Yu Miyake, MD, Sachiko Izumi, MD, PhD   +5 more
doaj  

Deep grey matter quantitative susceptibility mapping from small spatial coverages using deep learning [PDF]

arXiv, 2021
Introduction: Quantitative Susceptibility Mapping (QSM) is generally acquired with full brain coverage, even though many QSM brain-iron studies focus on the deep grey matter (DGM) region only. Reducing the spatial coverage to the DGM vicinity can substantially shorten the scan time or enhance the spatial resolution without increasing scan time; however,
arxiv  

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar, Arnold M. Evia, Mahir Tazwar, Sue E. Leurgans, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +6 more
wiley   +1 more source

Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36 [PDF]

, 2001
Kufor-Rakeb syndrome is an autosomal recessive nigro-striatal-pallidal-pyramidal neurodegeneration. The onset is in the teenage years with clinical features of Parkinson’s disease plus spasticity, supranuclear upgaze paresis, and dementia.
Al-Din, A., Bond, J., Crow, Y., Hampshire, D.J., Mubaidin, A., Roberts, E., Woods, C.G., Wriekat, A.L.   +7 more
core   +2 more sources

Patient Selection in Deep Brain Stimulation: A Role for Transcranial Direct Current Stimulation to Enhance the Levodopa Challenge?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dopaminergic medication and deep brain stimulation (DBS) improve motor symptoms in Parkinson's disease (PD), but levodopa response alone may not predict DBS outcomes. We retrospectively analyzed 19 PD patients undergoing levodopa challenges with and without prior transcranial direct current stimulation targeting a defined PD response network ...
Lukas L. Goede, Patricia Zvarova, Bahne H. Bahners, Andreas Horn   +3 more
wiley   +1 more source

Deep brain stimulation effect on anterior pallidum reduces motor impulsivity in Parkinson's disease

Brain Stimulation, 2022
Background: Deep Brain Stimulation (DBS) of the subthalamic nucleus or globus pallidus internus is used to treat the motor symptoms of Parkinson's disease.
Khaled Moussawi, Min Jae Kim, Sydney Baybayan, Myles Wood, Kelly A. Mills   +4 more
doaj  

Lesions causing post-stroke spasticity localize to a common brain network

Frontiers in Aging Neuroscience, 2022
ObjectiveThe efficacy of clinical interventions for post-stroke spasticity (PSS) has been consistently unsatisfactory, probably because lesions causing PSS may occur at different locations in the brain, leaving the neuroanatomical substrates of ...
Yin Qin, Yin Qin, Shuting Qiu, Shuting Qiu, Xiaoying Liu, Xiaoying Liu, Shangwen Xu, Xiaoyang Wang, Xiaoping Guo, Xiaoping Guo, Yuting Tang, Yuting Tang, Hui Li   +12 more
doaj   +1 more source