Results 71 to 80 of about 52,751 (312)
Neural indicators of fatigue in chronic diseases : A systematic review of MRI studies [PDF]
, 2018 The authors would like to thank the Sir Jules Thorn Charitable Trust for their financial support.Peer reviewedPublisher ...
Basu, Neil +3 more
core +3 more sources
Advanced Science, EarlyView.Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai +12 more
wiley +1 more source
Serum cholesterol and nigrostriatal R2* values in Parkinson's disease.
PLoS ONE, 2012 BackgroundThe occurrence of Parkinson's disease (PD) is known to be associated both with increased nigrostriatal iron content and with low serum cholesterol and PD, but there has been no study to determine a potential relationship between these two ...
Guangwei Du +6 more
doaj +1 more source
A Male Patient Showing Abnormal Gait and Dysarthria with Psychotic Symptoms
Türk Nöroloji Dergisi, 2020 Pantothenate kinase-associated neurodegeneration (PKAN) is a rare autosomal-recessive and neurodegenerative disorder associated with progressive motor impairment and mental deterioration.
Eu Jene Choi, Dong Goo Lee, Changxu Cui
doaj +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu +7 more
wiley +1 more source
A Stereotaxic Atlas of the Brain of the Chick (Gallus domesticus) [PDF]
, 1988 Nine brains taken from chicks two weeks of age were used for the development of this atlas. Each chick was first anesthetized with an intravenous (IV) injection of Chloropent2 (1.8 ml/kg).
Kuenzel, Wayne J., Masson, Manju
core +2 more sources
Preproenkephalin messenger RNA—containing neurons in striatum of patients with symptomatic and presymptomatic huntington's disease: An in situ hybridization study [PDF]
, 1991 Previous studies have revealed a loss of enkephalin immunoreactivity in the terminals of striatal neurons projecting to the external globus pallidus in patients with early grades of Huntington's disease (HD).
Albin +30 more
core +1 more source
ChemMedChem, Accepted Article.We report the discovery and characterization of a novel series of 4,4‐difluoropiperidine etherbased dopamine D4 receptor antagonists. Structure‐activity relationship studies led to the identification of compound 14a, which displays exceptional binding affinity for the D4 receptor (Ki = 0.3 nM) and remarkable selectivity over other dopamine receptor ...
Saeedeh Saeedi +3 more
wiley +1 more source
Development of Hyperkinesias after Long-term Pallidal Stimulation for Idiopathic Segmental Dystonia
Tremor and Other Hyperkinetic Movements, 2017 Background: Chronic deep brain stimulation (DBS) of the globus pallidus internus (GPi) has become an established treatment for dystonia. While bradykinetic symptoms may occur on chronic stimulation, the appearance of hyperkinetic movements has not ...
Andreas Wloch +5 more
doaj +1 more source
Frontiers in Public Health, 2022 BackgroundPrevious studies have linked internet use with several beneficial outcomes for brain health, but there is little data on this among older Chinese.ObjectiveThe goal of this study was to explore the association between internet use and cognitive ...
Wei Li +5 more
doaj +1 more source