Results 81 to 90 of about 56,426 (309)

Deep Brain Stimulation of Caudal Zona Incerta for Parkinson's Disease: One‐Year Follow‐Up and Electric Field Simulations

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective To evaluate the effects of bilateral caudal zona incerta (cZi) deep brain stimulation (DBS) for Parkinson's disease (PD) one year after surgery and to create anatomical improvement maps based on patient‐specific simulation of the electric field.
Rasmus Stenmark Persson   +6 more
wiley   +1 more source

Automated segmentation of cerebral deep gray matter from MRI scans: effect of field strength on sensitivity and reliability

open access: yesBMC Neurology, 2017
Background The cerebral subcortical deep gray matter nuclei (DGM) are a common, early, and clinically-relevant site of atrophy in multiple sclerosis (MS).
Renxin Chu   +3 more
doaj   +1 more source

How to run a brain bank. A report from the Austro-German brain bank [PDF]

open access: yes, 1993
The sophisticated analysis of and growing information on the human brain requires that acquisition, dissection, storage and distribution of rare material are managed in a professional way.
Gsell, W.   +9 more
core  

Lesions Associated With Autism Symptoms Map to a Cerebellar Brain Network in Tuberous Sclerosis Complex

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Autism spectrum disorder (ASD) affects 1 in 36 individuals in the United States and is characterized by impaired social communication and restrictive/repetitive behaviors. Individuals with tuberous sclerosis complex (TSC) have a high incidence of ASD (40%) and exhibit congenital brain lesions (tubers), offering a unique lesion‐based ...
Wendy Xiao Herman   +10 more
wiley   +1 more source

Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano   +10 more
wiley   +1 more source

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats

open access: yesNeurobiology of Disease, 2012
Huntington's disease (HD) is characterized by neuronal loss in the striatum, ultimately leading to an ‘imbalance’ in the electrical activity of the basal ganglia-thalamocortical circuits.
Rinske Vlamings   +8 more
doaj   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange   +8 more
wiley   +1 more source

Remembering Forward: Neural Correlates of Memory and Prediction in Human Motor Adaptation [PDF]

open access: yes, 2012
We used functional MR imaging (FMRI), a robotic manipulandum and systems identification techniques to examine neural correlates of predictive compensation for spring-like loads during goal-directed wrist movements in neurologically-intact humans ...
Houk, James   +6 more
core   +2 more sources

Home - About - Disclaimer - Privacy