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Quantitative assessment of glomerular basement membrane collagen IV α chains in paraffin sections from patients with focal segmental glomerulosclerosis and Alport gene variants. [PDF]
Puapatanakul P+10 more
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Glomerular Basement Membrane Autoantibodies
2014Partie 10, Chapitre 65 ; International ...
Luque-Paz, Damien+2 more
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Glomerular Basement Membrane [PDF]
The glomerular basement membrane shown in panel A differs from basement membranes in other locations in that it is faced by a cell layer on either side, namely the endothelia and the podocytes and that it is thicker, because it is the product of fusion of the basement membrane of endothelial cells and podocytes.
Jürgen Roth, Margit Pavelka
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Hereditary disorders of the glomerular basement membrane
Pediatric Nephrology, 1996Increased knowledge of the biochemical composition of the glomerular basement membrane (GBM) and the introduction of molecular genetics has shed new light on the hereditary disorders of the GBM. In this review three disorders are highlighted. About 85% of the cases reported as Alport syndrome are transmitted as the X-linked form and are due to ...
Smeets, H.J.M.+5 more
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Thin Glomerular Basement Membranes [PDF]
Fig 2. The diagnosis of thin basement membranes is made by electron microscopy. There is diffuse attenuation of the glomerular basement membrane, as illustrated here. In adults, basement membrane thickness less than 250 nm is indicative of thin basement membranes.
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Glomerular basement membrane as a compressible ultrafilter
Microvascular Research, 1989The ultrafiltration properties of isolated glomerular basement membrane were studied in vitro by forming membrane fragments into thin films for use as ultrafiltration membranes. The filtration properties of the films were examined using cytochrome c, myoglobin, lysozyme, ovalbumin, lactoglobulin, and serum albumin.
Robinson, G B, Walton, H A
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Anti-glomerular basement membrane vasculitis
Autoimmunity Reviews, 2023Antiglomerular basement membrane disease (anti-GBM) is a rare life-threatening autoimmune vasculitis that involves small vessels and it is characterized by circulating autoantibodies directed against type IV collagen antigens expressed in glomerular and alveolar basement membrane.
Claudio, Ponticelli+2 more
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VACUOLIZATION OF THE GLOMERULAR BASEMENT MEMBRANE
Acta Pathologica Microbiologica Scandinavica Section A Pathology, 1979Immunofluorescence and clinical data were collected retrospectively and renal tissue was examined by electron microscopy 1) for 20 consecutive patients whose glomeruli were normal in light microscopy except for vacuolization of obliquely‐cut portions of the glomerular basement membrane (GBM) after periodic acid‐silver‐methenamine staining, and 2) for ...
Amos Pasternack+3 more
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Dual origin of glomerular basement membrane
Developmental Biology, 1984The histogenesis of renal basement membranes was studied in grafts of avascular, 11-day-old mouse embryonic kidney rudiments grown on chick chorioallantoic membrane (CAM). Vessels of the chick CAM invade the mouse tissue during an incubation period of 7-10 days and eventually hybrid glomeruli composed of mouse epithelium and chick endothelium form ...
Sariola, H+6 more
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Antigens of the human glomerular basement membrane
Springer Seminars in Immunopathology, 1987The intent of the previous discussion has been to acquaint the reader with the recent expanding knowledge in matrix biochemistry and immunopathology as it pertains to the human GBM. However, it must be emphasized that the GBM antigens, which have yet to be characterized, may outnumber those that are currently defined.
Alfred F. Michael, Laurie S. Fouser
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