Results 201 to 210 of about 9,805,880 (332)

Promoting Equity in Transplant Research by Addressing the Exclusion of Patients With Glomerular Disease. [PDF]

Kidney Int Rep
Hullekes F, Verhoeff R, Lee SA, de Vries APJ, Seeger H, David-Neto E, Lee H, Malvezzi P, Loucaidou M, Verghese P, Thakur A, Manfro RC, La Manna G, Akalin E, Huang E, Me H, Villicana R, Poggio E, Wadei HM, Mansur J, Tedesco-Silva H, Kousios A, Wang AX, Gourishankar S, Mazzali M, Biancone L, Berger S, Stegall MD, Cravedi P, Riella LV.   +29 more
europepmc   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Elevated exposure to air pollutants accelerates primary glomerular disease progression. [PDF]

Clin Kidney J
Troost JP, Kshirsagar AV, Engel LS, O'Lenick CR, Smoyer WE, Klein J, Helmuth M, Mariani LH, Kretzler M, Smith AR, Lacey F, Trachtman H.   +11 more
europepmc   +2 more sources

Glomerular Disease in Patients With Acute Kidney Injury After Vancomycin Treatment-Need for Kidney Biopsy. [PDF]

Kidney Med
Kitamura M, Zardoost P, Satoskar AA.
europepmc   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Glomerular Disease and Cystic Kidney Disease: From Pathogenesis to Novel Therapeutic Approaches. [PDF]

Biomedicines
Filiopoulos V.
europepmc   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Editorial: Insights in glomerular disease. [PDF]

Front Nephrol
Chang B, Koirala A, Geetha D.
europepmc   +1 more source

Managing glomerular disease in pregnancy.

Nephrology, Dialysis and Transplantation, 2017
M. Hladunewich, K. Bramham, Belinda Jim, S. Maynard   +3 more
semanticscholar   +1 more source