Results 31 to 40 of about 9,805,880 (332)

Epidemiology of biopsy‐proven glomerular diseases in Chinese children: A scoping review

open access: yesChronic Diseases and Translational Medicine, 2022
Background Glomerular disease is the leading cause of chronic kidney disease globally. No scoping review reports have focused on China's spectrum of glomerular diseases in children.
Yetong Li   +5 more
doaj   +1 more source

CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease.

open access: yesAmerican Journal of Kidney Diseases, 2019
RATIONALE & OBJECTIVES Glomerular diseases, including minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, and immunoglobulin A (IgA) nephropathy, share clinical presentations, yet result from multiple biological mechanisms.
L. Mariani   +238 more
semanticscholar   +1 more source

Pathological spectrum of glomerular disease in patients with renal insufficiency: a single-center study in Northeastern China

open access: yesRenal Failure, 2019
Background: To investigate the pathological spectrum of glomerular disease in patients with renal insufficiency (RI) from 2008 to 2017. Methods and results: We calculated the estimated glomerular filtration rate (eGFR) with the Chronic Kidney Disease ...
Liangmei Chen   +8 more
doaj   +1 more source

Randomized Clinical Trial Design to Assess Abatacept in Resistant Nephrotic Syndrome

open access: yesKidney International Reports, 2018
Treatment-resistant nephrotic syndrome is a rare form of glomerular disease that occurs in children and adults. No Food and Drug Administration−approved treatments consistently achieve remission of proteinuria and preservation of kidney function.
Howard Trachtman   +11 more
doaj   +1 more source

The Risk of Severe Infections Following Rituximab Administration in Patients With Autoimmune Kidney Diseases: Austrian ABCDE Registry Analysis

open access: yesFrontiers in Immunology, 2021
ObjectiveTo characterize the incidence, type, and risk factors of severe infections (SI) in patients with autoimmune kidney diseases treated with rituximab (RTX).MethodsWe conducted a multicenter retrospective cohort study of adult patients with immune ...
Balazs Odler   +18 more
doaj   +1 more source

SGLT2 Inhibitors and the Diabetic Kidney [PDF]

open access: yes, 2016
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression ...
Busetto, Luca   +4 more
core   +1 more source

Podocyte-specific deletion of miR-146a increases podocyte injury and diabetic kidney disease

open access: yesFrontiers in Medicine, 2022
Diabetic glomerular injury is a major complication of diabetes mellitus and is the leading cause of end stage renal disease (ESRD). Healthy podocytes are essential for glomerular function and health.
Xiaobo Li   +10 more
doaj   +1 more source

Organoid single cell profiling identifies a transcriptional signature of glomerular disease.

open access: yesJCI Insight, 2019
Podocyte injury is central to many forms of kidney disease, but transcriptional signatures reflecting podocyte injury and compensation mechanisms are challenging to analyze in vivo.
J. Harder   +16 more
semanticscholar   +1 more source

Noninvasive Urinary Monitoring of Progression in IgA Nephropathy. [PDF]

open access: yes, 2019
Standard methods for detecting and monitoring of IgA nephropathy (IgAN) have conventionally required kidney biopsies or suffer from poor sensitivity and specificity.
Fervenza, Fernando C   +4 more
core   +1 more source

Factor B Inhibition with Iptacopan in Recurrent C3 Glomerulopathy Following Kidney Transplant: A Report of Two Cases

open access: yesKidney Medicine
C3 glomerulopathy is a rare disease caused by fluid phase dysregulation of the alternative complement pathway. Currently, treatment depends on clinical and histological severity and includes nephroprotection, unspecific immunosuppression, and terminal ...
Víctor J. Escudero-Saiz   +21 more
doaj   +1 more source

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