Results 51 to 60 of about 9,805,880 (332)

Direct-Acting Antiviral Agents for HCV-Associated Glomerular Disease and the Current Evidence

Pathogens, 2019
Glomerular disease is an extra-hepatic manifestation of hepatitis C virus infection (HCV) and membranoproliferative glomerulonephritis is the most frequent glomerular disease associated with HCV.
F. Fabrizi, R. Cerutti, Giulia Porata, P. Messa, E. Ridruejo   +4 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Relationship between Estimated Glomerular Filtration Rate (eGFR) and Metabolic Syndrome in Japanese [PDF]

, 2010
We investigated the link between renal function as evaluated by estimated glomerular filtration rate (eGFR) and metabolic syndrome in Japanese.
Makino, Hirofumi, Miyatake, Nobuyuki, Numata, Takeyuki, Shikata, Kenichi   +3 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK [PDF]

, 2018
Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an increased
Cardwell, J M, Holm, L P, Jepson, R E, O'Neill, D G, Stevens, K B, Walker, D J   +5 more
core   +2 more sources

Reduction in Renal Relapse and Preservation of Long‐Term Kidney Function After Lupus Low Disease Activity in Patients With Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE), but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung, Desmond Y. H. Yap, Ka Lai Lee, Philip H. Li, Iris Y. K. Tang, Chak Sing Lau, Shirley C. W. Chan   +6 more
wiley   +1 more source

PLASMIC score to aid diagnosis of aHUS: an analysis of C5 inhibitor clinical trials and the PINC AI™ healthcare database

BMC Nephrology
Background Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) that can lead to end organ damage and death without treatment.
Miguel G. Uriol-Rivera, Frank R. Ernst, John N. Booth, Àngels Comas, Christoph Gasteyger, Ioannis Tomazos, Ching Lum, Yan Wang, Ana I. Ávila   +8 more
doaj   +1 more source

Paraneoplastic glomerular disease. Case study

Клинический разбор в общей медицине, 2022
The case of membranous nephropathy manifested in nephrotic syndrome in a patient, newly diagnosed with lung cancer, is reported. Brief data on the paraneoplastic glomerular disease are provided, the need for cancer screening in elderly patients with ...
Leonid I. Dvoretsky, Nina A. Sidoruk, Sergei A. Krivushkin, Ekaterina S. Stolyarevich, Svetlana E. Kolendo, Andrei P. Stepanchenko   +5 more
doaj   +1 more source

Complications of Immunosuppression in Glomerular Disease.

American Society of Nephrology. Clinical Journal, 2018
Most glomerular diseases are immunologically mediated disorders of the kidney and are common causes of ESKD. In addition to supportive therapy, a wide range of immunosuppressive agents are used in the management of patients with these conditions ...
J. A. Jefferson
semanticscholar   +1 more source

Molecular Mechanisms in Early Diabetic Kidney Disease: Glomerular Endothelial Cell Dysfunction

International Journal of Molecular Sciences, 2020
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD), with prevalence increasing at an alarming rate worldwide and today, there are no known cures.
Emelie Lassén, Ilse S. Daehn
semanticscholar   +1 more source