International Journal of General Medicine, 2014 Katy E Trinkley,1 S Michelle Nikels,2 Robert L Page II,1 Melanie S Joy11Skaggs School of Pharmacy and Pharmaceutical Sciences, 2School of Medicine, University of Colorado, Aurora, CO, USA Objective: The purpose of this paper is to serve as a review for ...
Trinkley KE +3 more
doaj
Macromolecular Cystatin C Can Be a Caveat for Estimating Glomerular Filtration Rate in Biliary Obstruction [PDF]
, 2008 Liesbeth Vynckier +2 more
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Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Advanced Science, EarlyView.Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source
Estimating glomerular filtration rate in a population-based study
Vascular Health and Risk Management, 2010 Anoop Shankar1, Kristine E Lee2, Barbara EK Klein2, Paul Muntner3, Peter C Brazy4, Karen J Cruickshanks2,5, F Javier Nieto5, Lorraine G Danforth2, Carla R Schubert2,5, Michael Y Tsai6, Ronald Klein21Department of Community Medicine, West Virginia ...
Anoop Shankar +3 more
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One lithium level >1.0 mmol/L causes an acute decline in eGFR: findings from a retrospective analysis of a monitoring database [PDF]
, 2014 Objectives Lithium is a mainstay of bipolar disorder treatment, however, there are still differences in opinion on the effects of lithium use on renal function.
Anderson, Tim +5 more
core +1 more source
Prevalence of hypertension and decreased glomerular filtration rate in obese children: results of a population-based field study [PDF]
, 2013 Ali Düzova +4 more
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Advanced Science, EarlyView.This study presents a modular redox‐responsive nanocapsule platform that enables enhanced tumor‐targeted delivery of antimicrobial peptides. Using melittin as an example, the system achieves controlled activation within the tumor microenvironment, improving intratumoral accumulation while minimizing systemic toxicity.
Lin Tang +9 more
wiley +1 more source
The Comparison of Creatinine and Cystatin C Value in Preeclampsia Severity and Neonatal Outcome [PDF]
, 2016 Objectives: to compare the levels of creatinine and cystatin C with the severity of preeclampsia, and assess neonatal outcomes.Materials and Methods: Creatinine, cystatin C, and neonatal outcomes were assesed in 17 normotensive samples, 17 samples of ...
Wantania, J. (John) +1 more
core
Advanced Science, EarlyView.Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng +6 more
wiley +1 more source
Safety and efficacy of eculizumab in adult and pediatric patients with aHUS, with or without baseline dialysis [PDF]
, 2015 C
Hourmant, Maryvonne +5 more
core +1 more source