Results 171 to 180 of about 240,527 (296)

Physiological glomerular filtration rate and responses to Zeitgeber time and cold stress in C57BL/6 mice. [PDF]

Ren Fail
Wang X, Liu Y, Xin Y, Li H, Shen L, Xiao Y, Song Y, Liu L, Yu K, Wang C.   +9 more
europepmc   +1 more source

Mass Transport Mechanisms in 2D Laminar Nanofluidic Membranes for Separation and Energy Conversion

Carbon Innovation, EarlyView.
This review explores how two‐dimensional laminar membranes govern the transport of ions and molecules in confinement for advanced separation and energy conversion. By discussing how nanochannel architecture shapes membrane performance, this work highlights cation intercalation and functional modifications to improve osmotic energy harvesting ...
Adhy Prihatmiko Wibowo, Xiaojun Ren, Tongxi Lin, Rakesh Joshi   +3 more
wiley   +1 more source

Clearance of mannitol for assessment of glomerular filtration rate in chronic kidney disease: A validation against iohexol clearance. [PDF]

Clin Physiol Funct Imaging
Kiss K, Saeed A, Ricksten SE, Bragadottir G.   +3 more
europepmc   +1 more source

Effect of Late Second to Early Third Trimester of Pregnancy on the Activity of Renal Organic Anion Transporters (OAT1 and OAT3): A Biomarker Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnant individuals take drugs throughout pregnancy and many of these drugs (e.g., antivirals, antibiotics) are eliminated by renal organic anion transporters (OAT) 1 and OAT3. In vivo studies with OAT1/3 substrate drugs suggest that pregnancy increases renal OAT1/3 activities by 1.5‐ to 1.8‐fold.
Aarzoo Thakur, Jashvant D. Unadkat, Emily E. Fay, Nina Isoherranen, Mary F. Hebert   +4 more
wiley   +1 more source

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao, Jean G. Malavé, Joseph S. Rossi, Francesco Franchi, Ellen C. Keeley, Dominick J. Angiolillo, George A. Stouffer, Larisa H. Cavallari, Craig R. Lee   +8 more
wiley   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang, Dong‐Gyu Heo, Eunjin Hong   +2 more
wiley   +1 more source

Atherogenic index of plasma and lower estimated glomerular filtration rate in IgA nephropathy. [PDF]

Lipids Health Dis
Xu R, Qureshi AR, Suliman ME, Zhu N, Xu H, Chen Y, Zhong A, Wan Q, Lindholm B.   +8 more
europepmc   +1 more source

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

Drug Testing and Analysis, EarlyView.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz, Linus Korsmeier, Andreas Thomas, Mario Thevis   +3 more
wiley   +1 more source

Diagnostic Accuracy of Eight Estimated Glomerular Filtration Rate Equations for Assessing Kidney Function in Korean Pediatric Patients. [PDF]

Ann Lab Med
Kim H, Lee D, Choi Y, Jeong TD, Kim S, Lee W, Chun S.   +6 more
europepmc   +1 more source

Micronutrient Status in Children Suffering From Anorexia Nervosa: A Cohort of 349 Patients in a Referral Center for Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a serious illness in which more than half of all deaths are due to malnutrition. Critically low energy and protein intake are known causes of massive weight loss, whereas micronutrient deficiencies due to a low‐calorie food pattern remain poorly characterized in children with AN. Micronutrient deficiencies in
Zenaida Iordan, Diane Morfin, Marion Bernetiere, Marie Fauchet, Noël Peretti, Bérénice Segrestin, Pierre Poinsot   +6 more
wiley   +1 more source