Results 151 to 160 of about 240,527 (296)

Weighted distribution of glomerular filtration stages and frequency of proteinuria by glomerular filtration rate stage in the SABE Study of 2010.

Weighted distribution of glomerular filtration stages and frequency of proteinuria by glomerular filtration rate stage in the SABE Study of 2010.
Yeda Aparecida de Oliveira Duarte (7917758), Camila de Souza dos Santos (17721066), Dirce Maria Trevisan Zanetta (8321259)   +2 more
core   +1 more source

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen, Mathilde Rønne Koch, Cecilie Utke Rank, Christen Lykkegaard Andersen, Allan Weimann, Maria Thastrup, Tianwu Yang, Trine Meldgaard Lund, Ib Jarle Christensen, Flemming Nielsen, Tore Bjerregaard Stage, Sara Bisgaard Jensen, Mette Klarskov Andersen, Kjeld Schmiegelow, Kim Dalhoff   +14 more
wiley   +1 more source

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

British Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, Thea Laurentius, L. Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Incident Hypertension in Young Adults With a Mild Estimated Glomerular Filtration Rate Reduction. [PDF]

J Am Heart Assoc
Ahmed S, Hussain J, Grubic N, Akbari A, Ravani P, Tanuseputro P, Hundemer GL, Ramsay T, Tangri N, Bugeja A, Knoll GA, Maneul D, Sud M, Dhaliwal S, Chanchlani R, Sood MM.   +15 more
europepmc   +1 more source

EARLY DIAGNOSTIC AND PROGNOSTIC MARKERS OF CHRONIC KIDNEY DISEASE (CKD) IN CANINE AND FELINE PATIENTS

, 2011
SUMMARY Chronic kidney disease (CKD) is a clinical syndrome with a high prevalence both in human and veterinary medicine. Being able to formulate an early diagnosis of CKD can allow veterinarians to introduce a dietary and medical therapy, which can ...
LIPPI, ILARIA
core  

Estimated glomerular filtration rate in observational and interventional studies in chronic kidney disease

Estimated glomerular filtration rate is considered the principal measure of kidney function and, together with albuminuria, is a relevant prognostic factor for the development of end-stage kidney disease.
Coppolino, Giuseppe, Provenzano, Michele, Hu, Lilio, Abenavoli, Chiara, Cianciolo, Giuseppe, De Nicola, Luca, La Manna, Gaetano, Comai, Giorgia, Baraldi, Olga   +8 more
core   +1 more source

Codeine toxicity via breast Milk: Can this occur and implications for opiate therapy in children

British Journal of Clinical Pharmacology, EarlyView.
Codeine is commonly used in combination analgesic products. The use of codeine during breastfeeding can rarely be associated with serious adverse effects related to genetic polymorphisms affecting codeine's metabolism and disposition. Clinicians treating infants of breastfeeding mothers should be aware of this rare but potentially serious complication.
Michael Rieder
wiley   +1 more source

Impact of Estimated Glomerular Filtration Rate Equations on Vancomycin Dosing and Treatment Outcomes. [PDF]

Drug Des Devel Ther
Gu Q, Chen Y, Zhao A, Zhu H, Wang J, Kong M, Chen X, Liu Y, Zhang H, Chen D.   +9 more
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Correction: Prediction of estimated glomerular filtration rate slope and kidney prognosis of patients with chronic kidney disease. [PDF]

Sci Rep
Nagasu H, Nakashima T, Ihara K, Fujimori R, Goto T, Nitta D, Kishi S, Sasaki T, Kashihara N.   +8 more
europepmc   +1 more source