Results 181 to 190 of about 416,019 (379)

Diagnostic Value of Low-Molecular Mass Proteins in Serum for the Detection of Reduced Glomerular Filtration Rate [PDF]

, 1987
Klaus Jung, J.-H. Schulze, K Sydow, M Pergande, K Precht, G Schreiber   +5 more
openalex   +1 more source

Microtracer‐Based Assessment of the Mass Balance, Pharmacokinetics, and Excretion of [14C]Berzosertib, an Intravenous ATR Inhibitor, in Patients With Advanced Solid Tumors: A Phase 1 Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Berzosertib is a small‐molecule ataxia telangiectasia and Rad3‐related protein inhibitor. To assess the clearance mechanism(s) of berzosertib, a Phase 1, 2‐period, open‐label study was conducted in adults with advanced solid tumors who were treated with a single intravenous dose of 210 mg/m2 berzosertib containing approximately 3 µCi of [14C ...
Jayaprakasam Bolleddula, Holger Scheible, Florian Huber, Annick Seithel‐Keuth, Hanno Schieferstein, Deepthi S. Vagge, Nadra Mammasse, Eva Jaks, Jordi Ferrer, Camilo Moulin, Jennifer Dong, Karthik Venkatakrishnan, Zsuzsanna Papai   +12 more
wiley   +1 more source

A Joint Pharmacometric Model of Iohexol and Creatinine Administered through a Meat Meal to Assess GFR and Renal OCT2/MATE Activity

Clinical Pharmacology &Therapeutics, EarlyView.
Accurately assessing glomerular filtration rate (GFR) from plasma creatinine concentrations is challenging in patients with unstable renal function. This study aimed to refine the understanding of creatinine kinetics for more reliable assessments of GFR and net creatinine tubular secretion (nCTS) via OCT2/MATE in humans.
Zhendong Chen, Qian Dong, Charalambos Dokos, Jana Boland, Uwe Fuhr, Max Taubert   +5 more
wiley   +1 more source

How to estimate GFR in children [PDF]

, 2009
Delanghe, Joris
core   +1 more source

Synthesis of Radioactive Sodium 5-Acetamido-2, 4, 6-triiodo-N-methyl-isophthalamate (¹³¹I) and Its Application to External Measurement of Glomerular Filtration Rate in Rabbits

, 1968
Sadatake Kato, Kunio Kurata, Takao Wakabayashi, Yoshihiko SUGISAWA   +3 more
openalex   +2 more sources

The antihypertensive mechanism of verapamil. Alteration of glomerular filtration rate regulation. [PDF]

, 1988
Huabao Lin, David B. Young
openalex   +1 more source

Modeling and Simulation to Inform Apixaban Dosing in Pediatrics With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Treated With Asparaginase

Clinical Pharmacology &Therapeutics, EarlyView.
Apixaban could be a potential treatment option for the prevention of venous thromboembolism (VTE) in children with acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LL). This analysis describes an updated two‐compartment population pharmacokinetic (PPK) model that characterizes the PK variability of apixaban in pediatric patients with ALL ...
Praneeth Jarugula, Toni Ajavon‐Hartmann, Obinna Obianom, Elizabeth Ludwig, Christina Crevar, David Marchisin, Zhaoqing Wang, Weidong Chen, Bing He, Lesley G. Mitchell, Vilmarie Rodriguez, Glen Lew, Vidya Perera, Bindu Murthy, Samira Merali   +14 more
wiley   +1 more source

A METHOD FOR THE URETERAL CATHETERIZATION AND THE DETERMINATION OF THE GLOMERULAR FILTRATION RATE IN RATS; WITH SOME APPLICATIONS ON THE STUDY OF PARATHYROIDS

, 1962
Mikio Shikita
openalex   +2 more sources

Effect of low dose 1 alpha-hydroxycholecalciferol on glomerular filtration rate in moderate renal failure. [PDF]

, 1983
FU Eke, M H Winterborn
openalex   +1 more source

Estimating glomerular filtration rate for the full age spectrum from serum creatinine and cystatin C

Nephrology, Dialysis and Transplantation, 2017
H. Pottel, P. Delanaye, E. Schaeffner, L. Dubourg, B. Eriksen, T. Melsom, E. Lamb, A. Rule, S. Turner, R. Glassock, V. D. de Souza, L. Selistre, K. Goffin, S. Pauwels, C. Mariat, M. Flamant, Natalie Ebert   +16 more
semanticscholar   +1 more source