ABSTRACT Pharmacokinetics is the study of the movement of drug in the body and includes the processes of absorption, distribution, metabolism, and excretion. Pharmacodynamics is the pharmacologic effect of the drug on the body. The pharmacokinetics of a drug determines its pharmacologic effect. Pharmacokinetic studies describe drug concentrations while
Heather K. Knych
wiley +1 more source
Utilizing gentamicin concentrations to estimate glomerular filtration rate in intensive care unit patients. [PDF]
Smekal AK+5 more
europepmc +1 more source
Relationship between glomerular filtration rate and maximum tubular reabsorptive rate of glucose
Tung-Fan Kwong, Cleaves M. Bennett
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Role of selenium in the pathophysiology of cardiorenal anaemia syndrome
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai+2 more
wiley +1 more source
Chronic kidney disease in geriatric patients: Estimating glomerular filtration rate in older patients with comorbidities. [PDF]
Gembillo G, Soraci L, Santoro D.
europepmc +1 more source
A BASIC STUDY OF THE HANSSEN TECHNIQUE FOR EVALUATION OF SINGLE NEPHRON GLOMERULAR FILTRATION RATE
Shigeomi Kuroda+6 more
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Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang+7 more
wiley +1 more source
Individualized calibration of estimated glomerular filtration rate for serial renal function determination: a pilot study. [PDF]
Mekonnen BW+4 more
europepmc +1 more source
Are Cystatin C and β2-Microglobulin Better Markers than Serum Creatinine for Prediction of a Normal Glomerular Filtration Rate in Pediatric Subjects? [PDF]
Guido Filler+4 more
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Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya+9 more
wiley +1 more source