Results 221 to 230 of about 435,208 (390)

Effect of truncating blood sampling in measuring glomerular filtration rate. [PDF]

open access: yesAm J Nucl Med Mol Imaging
Nichols KJ   +4 more
europepmc   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel   +13 more
wiley   +1 more source

Electronic Patient File‐Embedded Model‐Informed Precision Dosing Compared with Physician Dosing of Tacrolimus in Kidney Transplantation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Model‐informed precision dosing (MIPD) of tacrolimus in renal allograft recipients, evaluated in silico, demonstrated improved (time to and) probability of target concentration attainment and smaller deviations from target range. Using simulated tacrolimus concentration‐time profiles, a study of 200 patients was predicted to have sufficient power to ...
Dirk R.J. Kuypers   +6 more
wiley   +1 more source

Microbes and GFR in Health and CKD in Mice. [PDF]

open access: yesJ Am Soc Nephrol
Xu J   +11 more
europepmc   +1 more source

Association between estimated glomerular filtration rate and sodium excretion in urine of African descendants in Brazil: a population-based study

open access: gold, 2018
Elisângela Milhomem Dos Santos   +5 more
openalex   +1 more source

Low-Dose Aspirin Therapy in Patients With Type 2 Diabetes and Reduced Glomerular Filtration Rate [PDF]

open access: hybrid, 2011
Yoshihiko Saito   +11 more
openalex   +1 more source

Model‐Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Model‐informed drug development (MIDD) played a crucial role in the successful development and regulatory approval of daprodustat, a novel oral hypoxia‐inducible factor prolyl hydroxylase (HIF‐PHI) inhibitor aimed at treating anemia in chronic kidney disease patients.
Kelly M. Mahar   +6 more
wiley   +1 more source

Comparison of different equations for estimating the glomerular filtration rate in pediatric kidney transplant recipients. [PDF]

open access: yesPediatr Nephrol
Sukboonthong P   +11 more
europepmc   +1 more source

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