Results 101 to 110 of about 16,029 (237)
Influence of dietary protein on glomerular filtration before and after bariatric surgery: a cohort study [PDF]
BACKGROUND: Obesity-associated elevations in glomerular filtration rate (GFR) are common and may play a role in the development of kidney disease, so identifying the underlying mechanism is important. We therefore studied whether reductions in dietary
Friedman, Allon N.+5 more
core +1 more source
ABSTRACT Why donate a kidney to a stranger? The history of living nondirected kidney donation, so‐called altruistic or Good Samaritan donation, is notable for its associated skepticism if not outright rejection. Since its possibility, transplantation institutes have been concerned over the motives of individuals who present to their clinics with the ...
Robert M. Guerin, Lutz Götzmann
wiley +1 more source
Obesity and kidney protection [PDF]
Context: Obesity, both directly and indirectly, increases the risk for a variety of disease conditions including diabetes, hypertension, liver disease, and certain cancers, which in turn, decreases the overall lifespan in both men and women.
Aravind Chandra+2 more
doaj +1 more source
A Translational Study of the Correlation Between Low Birth Weight, Hypertension, and Kidney Function Using a Rat Model [PDF]
We studied the correlation between low birth weight, hypertension, and kidney function using a rat model. There is a strong correlation between these three phenomena especially in the Southeastern United States and in non-White populations.
Daniels, Marcus
core +1 more source
Gender differences in renal responses to hyperglycemia and angiotensin-converting enzyme inhibition in diabetes [PDF]
Gender differences in renal responses to hyperglycemia and angiotensin-converting enzyme inhibition in diabetes.BackgroundDiabetes mellitus reduces female gender-mediated protection against progression of renal disease but the mechanisms responsible for ...
Cherney, David Z.I.+2 more
core +1 more source
A validated disease progression model quantified eGFR decline in T2DM patients with and without DN. Cardiovascular comorbidities and poor glycaemic control accelerated decline, while ARBs, statins, and metformin attenuated it. The model supports early, consistent use of these therapies to preserve renal function and guide individualized risk‐based ...
Sohail Aziz+2 more
wiley +1 more source
The effects of dual PPARα/γ agonism compared with ACE inhibition in the BTBRob/ob mouse model of diabetes and diabetic nephropathy [PDF]
The leptin-deficient BTBRob/ob mouse develops progressive albuminuria and morphological lesions similar to human diabetic nephropathy (DN), although whether glomerular hyperfiltration, a recognized feature of early DN that may contribute to renal injury,
Böttcher, G+11 more
core +1 more source
Obesity‐related glomerulopathy: How it happens and future perspectives
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey+7 more
wiley +1 more source
Kidney Hyperfiltration After Nephrectomy: A Mechanism to Restore Kidney Function in Living Donors
Living donor kidney transplantation (LDKT) is the treatment of choice for patients with end stage renal disease (ESRD). Up to now, the studies reporting the impact of nephrectomy in living kidney donors to their future kidney function were limited.
Maruhum Bonar Marbun, Endang Susalit
doaj
OBJECTIVE: To analyze the blood pressure patterns in normoalbuminuric IDDM patients with glomerular hyperfiltration. PATIENTS AND METHODS: A controlled cross-sectional study of 38 normotensive normoalbuminuric (urinary albumin excretion rate 134 ml ...
Miriam Pecis+2 more
doaj