Results 101 to 110 of about 169,139 (203)

Glomerular hyperfiltration is associated with blood pressure abnormalities in normotensive normoalbuminuric IDDM patients

open access: yesClinical and Biomedical Research, 2022
OBJECTIVE: To analyze the blood pressure patterns in normoalbuminuric IDDM patients with glomerular hyperfiltration. PATIENTS AND METHODS: A controlled cross-sectional study of 38 normotensive normoalbuminuric (urinary albumin excretion rate 134 ml ...
Miriam Pecis   +2 more
doaj  

Determination of the best method to estimate glomerular filtration rate from serum creatinine in adult patients with sickle cell disease: a prospective observational cohort study

open access: yesBMC Nephrology, 2012
Background Sickle cell disease (SCD) leads to tissue hypoxia resulting in chronic organ dysfunction including SCD associated nephropathy. The goal of our study was to determine the best equation to estimate glomerular filtration rate (GFR) in SCD adult ...
Arlet Jean-Benoît   +10 more
doaj   +1 more source

Beneficial Impact of Kaempferol on Kidney Function and Long‐Term Prognosis in Overweight or Obese Adults

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Higher kaempferol intake is associated with reduced kidney damage prevalence and improved long‐term survival in overweight or obese adults. Each 5 mg/day increase in dietary kaempferol correlates with a 7% lower risk of kidney impairment and a 7% decrease in mortality over a median 117‐month follow‐up.
Lin Shi, Yiquan Sang
wiley   +1 more source

Gambaran eGFR Menurut CKD-EPI pada Penderita Thalassemia Mayor di Rumah Sakit Dr. Hasan Sadikin Bandung

open access: yesMajalah Kedokteran Bandung, 2017
Increased life expectancy of thalassemia patients has a consequence of various manifestations of the diseases in many organs including kidney. Estimated glomerular filtration rate (eGFR) can be used for detecting early renal dysfunctions due to the fact ...
Rismauli Doloksaribu   +2 more
doaj   +1 more source

A Rational Approach to Pharmacotherapy in Pregnancy

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen   +2 more
wiley   +1 more source

Protein-induced glomerular hyperfiltration: Role of hormonal factors

open access: yesKidney International, 1988
High protein diets acutely elevate the glomerular filtration rate. To characterize this response we administered 1 g of protein/kg body weight as a beef steak meal to nine, healthy male subjects and measured glomerular filtration rate (inulin clearance), renal plasma flow (p-amino hippurate clearance), plasma renin activity, aldosterone and plasma and ...
Krishna, G. Gopal   +7 more
openaire   +2 more sources

Eplerenone improves kidney function and cardiac performance in obese male mice

open access: yesDiabetic Medicine, Volume 43, Issue 1, January 2026.
Abstract Aims Renin‐angiotensin‐aldosterone system (RAAS) activation mediates obesity‐associated cardiorenal dysfunction. Due to an incomplete understanding of the molecular mechanisms, the clinical use of RAAS antagonism in obesity‐associated cardiometabolic complications remains uncertain.
Ayman K. Banah   +8 more
wiley   +1 more source

Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 16-26, January 2026.
Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle   +3 more
wiley   +1 more source

Exploring Bilirubin’s Impact on Autophagy and Apoptosis in Diabetic Kidney Disease

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Background Diabetic kidney disease (DKD) affects nearly half of patients with type 1 or type 2 diabetes and is a leading cause of end‐stage renal disease (ESRD). Maladaptive autophagy and increased apoptosis have been observed in diabetic kidneys. Bilirubin, a natural antioxidant, may exert protective effects against DKD progression; however, the ...
Mohammad Hasan Maleki   +9 more
wiley   +1 more source

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