Results 101 to 110 of about 169,139 (203)
OBJECTIVE: To analyze the blood pressure patterns in normoalbuminuric IDDM patients with glomerular hyperfiltration. PATIENTS AND METHODS: A controlled cross-sectional study of 38 normotensive normoalbuminuric (urinary albumin excretion rate 134 ml ...
Miriam Pecis +2 more
doaj
Background Sickle cell disease (SCD) leads to tissue hypoxia resulting in chronic organ dysfunction including SCD associated nephropathy. The goal of our study was to determine the best equation to estimate glomerular filtration rate (GFR) in SCD adult ...
Arlet Jean-Benoît +10 more
doaj +1 more source
Higher kaempferol intake is associated with reduced kidney damage prevalence and improved long‐term survival in overweight or obese adults. Each 5 mg/day increase in dietary kaempferol correlates with a 7% lower risk of kidney impairment and a 7% decrease in mortality over a median 117‐month follow‐up.
Lin Shi, Yiquan Sang
wiley +1 more source
Increased life expectancy of thalassemia patients has a consequence of various manifestations of the diseases in many organs including kidney. Estimated glomerular filtration rate (eGFR) can be used for detecting early renal dysfunctions due to the fact ...
Rismauli Doloksaribu +2 more
doaj +1 more source
A Rational Approach to Pharmacotherapy in Pregnancy
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen +2 more
wiley +1 more source
The Physiology of Lived Experience: And then there was one – the story of a radical nephrectomy
Experimental Physiology, EarlyView.
Michael J. Shattock
wiley +1 more source
Protein-induced glomerular hyperfiltration: Role of hormonal factors
High protein diets acutely elevate the glomerular filtration rate. To characterize this response we administered 1 g of protein/kg body weight as a beef steak meal to nine, healthy male subjects and measured glomerular filtration rate (inulin clearance), renal plasma flow (p-amino hippurate clearance), plasma renin activity, aldosterone and plasma and ...
Krishna, G. Gopal +7 more
openaire +2 more sources
Eplerenone improves kidney function and cardiac performance in obese male mice
Abstract Aims Renin‐angiotensin‐aldosterone system (RAAS) activation mediates obesity‐associated cardiorenal dysfunction. Due to an incomplete understanding of the molecular mechanisms, the clinical use of RAAS antagonism in obesity‐associated cardiometabolic complications remains uncertain.
Ayman K. Banah +8 more
wiley +1 more source
Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review
Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle +3 more
wiley +1 more source
Exploring Bilirubin’s Impact on Autophagy and Apoptosis in Diabetic Kidney Disease
Background Diabetic kidney disease (DKD) affects nearly half of patients with type 1 or type 2 diabetes and is a leading cause of end‐stage renal disease (ESRD). Maladaptive autophagy and increased apoptosis have been observed in diabetic kidneys. Bilirubin, a natural antioxidant, may exert protective effects against DKD progression; however, the ...
Mohammad Hasan Maleki +9 more
wiley +1 more source

