Impact of sotagliflozin on glomerular hyperfiltration in people with type 1 diabetes: A post hoc analysis of the inTandem3 trial. [PDF]
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1537-1540, February 2026.
Pathak A +4 more
europepmc +4 more sources
Association of Glomerular Hyperfiltration and Cardiovascular Risk in Middle-Aged Healthy Individuals. [PDF]
Key Points Question Is glomerular hyperfiltration associated with future cardiovascular events in healthy individuals? Findings In this cohort study of 9515 patients with health information accessed through the CARTaGENE research platform, glomerular ...
Dupuis ME +4 more
europepmc +3 more sources
Glomerular hyperfiltration and β-2 microglobulin as biomarkers of incipient renal dysfunction in cancer survivors. [PDF]
Herein, we aimed to evaluate the occurrence of impaired renal function after cancer treatment with potentially nephrotoxic chemotherapy in children.
Tibúrcio FR +3 more
europepmc +4 more sources
Sub-morbid dehydration-associated glomerular hyperfiltration: An emerging reality? [PDF]
Background : Severe dehydration decreases renal perfusion. However, it is unclear whether sub-morbid dehydration affects kidney function similarly.
Hyang Ki Min +3 more
doaj +3 more sources
Recently, we reported a mutation in γ-Adducin (ADD3) was associated with an impaired myogenic response of the afferent arteriole and hypertension-induced chronic kidney disease (CKD) in FHH rats. However, the mechanisms by which altered renal blood flow (
Fan L +6 more
europepmc +4 more sources
Early Glomerular Hyperfiltration and Long-Term Kidney Outcomes in Type 1 Diabetes: The DCCT/EDIC Experience. [PDF]
BACKGROUND AND OBJECTIVES Glomerular hyperfiltration has been considered to be a contributing factor to the development of diabetic kidney disease (DKD).
Molitch ME +10 more
europepmc +3 more sources
Association between metabolic parameters and glomerular hyperfiltration in a representative Korean population without chronic kidney disease. [PDF]
AimsTo investigate associations of glomerular hyperfiltration with other metabolic factors in a nationally representative dataset.MethodsWe analyzed cross-sectional data from 15,918 subjects with estimated glomerular filtration rate (eGFR) >60 ml/min/1 ...
Sangmo Hong +6 more
doaj +3 more sources
Back to the Future: Glomerular Hyperfiltration and the Diabetic Kidney. [PDF]
Observations that early changes in renal hemodynamics beget later kidney damage was a seminal scientific discovery that ultimately led to development of the only class of agents, inhibitors of the renin-angiotensin system (ACE inhibitors and angiotensin ...
Tuttle KR.
europepmc +4 more sources
Longitudinal study of glomerular hyperfiltration in adults with sickle cell anemia: a multicenter pooled analysis. [PDF]
Glomerular hyperfiltration is common in young sickle cell anemia patients and precedes development of overt kidney disease. In this multicenter pooled cohort, we characterized hyperfiltration and its decline to normal range in adult patients.
Ataga KI +10 more
europepmc +2 more sources
Renal Dysfunction in Prediabetes: Confirmed by Glomerular Hyperfiltration and Albuminuria. [PDF]
Objectives Prediabetes is defined as an intermediate state of hyperglycemia with glucose levels above normal but below the diagnostic cutoff of diabetes mellitus.
Shilpasree AS +4 more
europepmc +2 more sources

