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Increased Measured GFR and Proteinuria in Children with Previous Infection by SARS-CoV-2: Should We Be Concerned? [PDF]
Marcellino A+9 more
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Nutritional treatment in chronic kidney disease: the concept of nephroprotection. [PDF]
Di Nuzzi A+2 more
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Nature Reviews Nephrology, 2022
Circulating blood is filtered across the glomerular barrier to form an ultrafiltrate of plasma in the Bowman's space. The volume of glomerular filtration adjusted by time is defined as the glomerular filtration rate (GFR), and the total GFR is the sum of all single-nephron GFRs.
Monica Cortinovis+4 more
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Circulating blood is filtered across the glomerular barrier to form an ultrafiltrate of plasma in the Bowman's space. The volume of glomerular filtration adjusted by time is defined as the glomerular filtration rate (GFR), and the total GFR is the sum of all single-nephron GFRs.
Monica Cortinovis+4 more
openaire +2 more sources
Development of glomerular hyperfiltration, a multiphasic phenomenon
American Journal of Physiology-Renal Physiology, 2020The trajectory of glomerular filtration rate (GFR) in relation to glomerular hyperfiltration (GHF) has been unknown. It was evaluated retrospectively in 23,982 GHF-free health examinees who were followed for 2−10 yr (mean: 5.1 yr). GFR was estimated by the serum creatinine concentration, and GHF was defined as age- and sex-specific estimated GFR (eGFR)
Yasuho Shimada+10 more
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Glomerular hyperfiltration in excess weight adolescents
Nigerian Journal of Clinical Practice, 2019Childhood overweight/obesity burden is on the rise worldwide. Obesity affects virtually all organs. In the kidney, glomerular hyperfiltration that manifests as elevated glomerular filtration rate is a frequent manifestation in obesity. This adaptive renal manifestation to excess metabolic demand on the kidney, in children, has been studied mainly in ...
MO Ibadin+4 more
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Kinin, a Mediator of Diabetes-Induced Glomerular Hyperfiltration
Diabetes, 1995Renal kallikrein is increased in diabetic patients and streptozotocin (STZ)-induced diabetic rats with hyperflltration. Chronic inhibition of renal kallikrein reduces glomerular filtration rate (GFR) and renal plasma flow (RPF) in hyperfiltering STZ-induced diabetic rats.
Ayad A. Jaffa+2 more
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Glomerular Hyperfiltration in Human Diabetes
Diabetes Care, 1994The presence of the characteristic early glomerular hyperfiltration seenin diabetes was originally suggested long ago by Cambier (1), indeed a few years before the well-known studies by Kimmelstiel and Wilson (2) that documented the typical glomerular structural lesions in diabetic patients. Brenner (3,4), in his breakthrough glomerular hyperfiltration-
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Abnormalities of Glomerular Eicosanoid Metabolism in States of Glomerular Hyperfiltration
1989The glomerulus is a complex structure that functions primarily to produce an ultrafiltrate of plasma. Micropuncture studies in the Munich-Wistar rat have identified the major physical determinants of the glomerular filtration rate (GFR): glomerular plasma flow; afferent protein concentration; transcapillary hydraulic-pressure difference; and the ...
Morris Schambelan+11 more
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Glomerular hyperfiltration: definitions, mechanisms and clinical implications
Nature Reviews Nephrology, 2012Glomerular hyperfiltration is a phenomenon that can occur in various clinical conditions including kidney disease. No single definition of glomerular hyperfiltration has been agreed upon, and the pathophysiological mechanisms, which are likely to vary with the underlying disease, are not well explored.
Berenice Reed-Gitomer+3 more
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