Longitudinal study of glomerular hyperfiltration and normalization of estimated glomerular filtration in adults with sickle cell disease. [PDF]
Glomerular hyperfiltration is common in sickle cell disease (SCD) and precedes proteinuria and declining kidney function. We evaluated hyperfiltration in SCD patients and its “normalization.” Routine visit data were collected retrospectively from adult ...
Derebail VK +4 more
europepmc +2 more sources
Association Between Blunted Glomerular Hyperfiltration in Pregnancy and Severe Maternal Morbidity—A Research Letter [PDF]
Background: Glomerular hyperfiltration is one physiological adaptation to pregnancy, marked by a decline in serum creatinine (SCr) concentration by 16 weeks’ gestation.
Ziv Harel, Alison L. Park, Joel G. Ray
doaj +2 more sources
High sodium intake, glomerular hyperfiltration, and protein catabolism in patients with essential hypertension. [PDF]
Aims A blood pressure (BP)-independent metabolic shift towards a catabolic state upon high sodium (Na+) diet, ultimately favouring body fluid preservation, has recently been described in pre-clinical controlled settings. We sought to investigate the real-
Rossitto G +20 more
europepmc +2 more sources
Pharmacokinetic relevance of glomerular hyperfiltration for drug dosing. [PDF]
ABSTRACT In chronic kidney disease (CKD) patients, hypofiltration may lead to the accumulation of drugs that are cleared mainly by the kidney and, vice versa, hyperfiltration may cause augmented renal excretion of the same drugs. In this review we mainly focus on the issue of whether hyperfiltration significantly impacts the renal ...
Zoccali C, Mallamaci F, De Caterina R.
europepmc +3 more sources
The Relationship of Alcohol Consumption and Drinking Pattern to the Risk of Glomerular Hyperfiltration in Middle-aged Japanese Men: The Kansai Healthcare Study [PDF]
Background: Glomerular hyperfiltration has been reported to be associated with adverse renal outcomes in the general population. It is not known whether drinking pattern is associated with the risk of glomerular hyperfiltration in healthy individuals ...
Mikiko Shibata +8 more
doaj +2 more sources
Prevalence and associated factors of glomerular hyperfiltration among adult stable sickle cells in Kinshasa, DR Congo [PDF]
Introduction Glomerular hyperfiltration is highly frequent, theoretically dependent on cardiac output, low systemic vascular resistance and hemolysis markers. In sickle cell disease (SCD), hyperfiltration is an extremely common phenomenon and occurred in
Yannick Engole Mompango +16 more
doaj +2 more sources
PM2.5 Exposure Induces Glomerular Hyperfiltration in Mice in a Gender-Dependent Manner [PDF]
As one of the most common air pollutants, fine particulate matter (PM2.5) increases the risk of diseases in various systems, including the urinary system. In the present study, we exposed male and female C57BL/6J mice to PM2.5 for 8 weeks. Examination of
Hao Wang +5 more
doaj +2 more sources
Glomerular hyperfiltration in patients with severe trauma
Background and objective: Augmented renal clearance or glomerular hyperfiltration (GHF) can significantly affect the clinical outcomes of renally eliminated drugs by promoting subtherapeutic drug exposure.
Luisa María Charco Roca +2 more
doaj +3 more sources
Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial. [PDF]
Obesity is an important risk factor for the development of chronic kidney disease. One of the major factors involved in the pathogenesis of obesity-associated kidney disease is glomerular hyperfiltration.
Boris Zingerman +7 more
doaj +3 more sources
GLOMERULAR HYPERFILTRATION – CAUSES AND CONSEQUENCES [PDF]
he daily filtration of about 180 litters of virtually proteinfree fluid from plasma is the hallmark of the kidney`s excretory function and the initial step in urine formation.
Y. Ammar
semanticscholar +2 more sources

