Glomerular hyperfiltration as a therapeutic target for CKD. [PDF]
Nephrol Dial TransplantABSTRACT The global burden of chronic kidney disease (CKD) is high and increasing. Early diagnosis and intervention are key to improve outcomes. Single-nephron glomerular hyperfiltration is an early pathophysiologic manifestation of CKD that may result in absolute glomerular hyperfiltration, i.e.
Kanbay M +5 more
europepmc +3 more sources
Glomerular Hyperfiltration and Albuminuria in Critically ILL Patients [PDF]
Anaesthesia and Intensive Care, 2008 Glomerular hyperfiltration and albuminuria are two pathological conditions that could alter renal drug elimination, but they have been rarely studied in a critical care setting. The aims of this descriptive, prospective study performed on 89 critically ill patients are to determine rates of glomerular hyperfiltration (main objective) and albuminuria (
Óscar Fuster +3 more
openalex +4 more sources
Glomerular hyperfiltration may be a novel risk factor of restrictive spirometry pattern: Analysis of the Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2015. [PDF]
PLoS One, 2019 Lim HI, Jun SJ, Lee SW.
europepmc +3 more sources
Abdominal Adipose Tissue was Associated with Glomerular Hyperfiltration among Non- Diabetic and Normotensive Adults with a Normal Body Mass Index. [PDF]
PLoS ONE, 2015 Glomerular hyperfiltration is recognized as an early marker of progressive kidney dysfunction in the obese population. This study aimed to identify the relationship between glomerular hyperfiltration and body fat distribution measured by computed ...
Jeonghwan Lee +8 more
doaj +1 more source
Consequences of intrauterine growth restriction for the kidney [PDF]
, 2006 Low birth weight due to intrauterine growth restriction is associated with various diseases in adulthood, such as hypertension, cardiovascular disease, insulin resistance and end-stage renal disease.
Delemarre-van de Waal, H.A. (Henriette) +2 more
core +13 more sources
Glomerular hyperfiltration in prediabetes and prehypertension [PDF]
Nephrology Dialysis Transplantation, 2011 This study aimed to investigate the associations of hyperfiltration and hypofiltration with prediabetes and prehypertension.The study subjects included 99 140 people aged 20-89 years who underwent health checkups in Aichi Prefecture, Japan. The prevalence of hyperfiltration [estimated glomerular filtration rate (eGFR) above the age-/sex-specific 95th ...
Yoshinari Yasuda +5 more
openaire +3 more sources
Glomerular filtration rate abnormalities in sickle cell disease
Frontiers in Medicine, 2022 Sickle cell disease (SCD) is a group of inherited blood disorders affecting the β-globin gene, resulting in the polymerization of hemoglobin and subsequent sickling of the red blood cell.
Nowah Afangbedji, Marina Jerebtsova
doaj +1 more source
BMC Nephrology, 2022 Background Obesity is one of the causes of glomerular hyperfiltration. Studies on the relationship between body fat content and glomerular hyperfiltration have been limited to special children.
Yongchang Yang, Yubin Wu
doaj +1 more source
Frontiers in Pharmacology, 2021 Large-scale clinical outcome studies demonstrated the efficacy of SGLT2 inhibitors in patients with type II diabetes. Besides their therapeutic efficacy in diabetes, significant renoprotection was observed in non-diabetic patients with chronic kidney ...
Philipp Tauber +9 more
doaj +1 more source
Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial. [PDF]
PLoS ONE, 2015 Obesity is an important risk factor for the development of chronic kidney disease. One of the major factors involved in the pathogenesis of obesity-associated kidney disease is glomerular hyperfiltration.
Boris Zingerman +7 more
doaj +1 more source