Results 31 to 40 of about 16,029 (237)

Relative Glomerular Hyperfiltration in Primary Aldosteronism [PDF]

Journal of the American Society of Nephrology, 2005
Experimental and clinical data suggest that primary aldosteronism (PA) may be associated with cardiovascular hypertrophy and fibrosis, in part independent of the BP level. Whether PA may also result in specific deleterious effects on the kidneys was less studied.
Pierre Fesler, Guilhem du Cailar, Albert Mimran, Jean Ribstein   +3 more
openaire   +2 more sources

Glomerular Biomechanical Stress and Lipid Mediators during Cellular Changes Leading to Chronic Kidney Disease

Biomedicines, 2022
Hyperfiltration is an important underlying cause of glomerular dysfunction associated with several systemic and intrinsic glomerular conditions leading to chronic kidney disease (CKD).
Mukut Sharma, Vikas Singh, Ram Sharma, Arnav Koul, Ellen T. McCarthy, Virginia J. Savin, Trupti Joshi, Tarak Srivastava   +7 more
doaj   +1 more source

Glomerular Hyperfiltration in Hypertensive African Americans [PDF]

Hypertension, 2000
Abstract —The incidence of end-stage renal disease attributable to hypertension is 5-fold greater in African Americans than in whites. To determine whether glomerular hyperfiltration is an antecedent to renal failure, we compared responses of renal blood flow and glomerular filtration rate to graded infusions of ...
Daniel Gaudet, Jane Morley Kotchen, Theodore A. Kotchen, Andrew W. Piering, Pavel Hamet, Allen W. Cowley, Clarence E. Grim, Richard J. Roman, Mary L. Kaldunski   +8 more
openaire   +3 more sources

Proximal tubular hypertrophy and enlarged glomerular and proximal tubular urinary space in obese subjects with proteinuria. [PDF]

PLoS ONE, 2013
BACKGROUND: Obesity is associated with glomerular hyperfiltration, increased proximal tubular sodium reabsorption, glomerular enlargement and renal hypertrophy.
Ana Tobar, Yaacov Ori, Sydney Benchetrit, Gai Milo, Michal Herman-Edelstein, Boris Zingerman, Netta Lev, Uzi Gafter, Avry Chagnac   +8 more
doaj   +1 more source

Back to the Future: Glomerular Hyperfiltration and the Diabetic Kidney. [PDF]

Diabetes, 2017
Observations that early changes in renal hemodynamics beget later kidney damage was a seminal scientific discovery that ultimately led to development of the only class of agents, inhibitors of the renin-angiotensin system (ACE inhibitors and angiotensin receptor blockers), approved by regulatory agencies for the treatment of diabetic kidney disease ...
Tuttle KR.
europepmc   +5 more sources

A systematic review of glomerular hyperfiltration assessment and definition in the medical literature.

Clin J Am Soc Nephrol, 2015
Cachat F, Combescure C, Cauderay M, Girardin E, Chehade H.   +4 more
europepmc   +2 more sources

Renal Hyperfiltration and the Development of Microalbuminuria in Type 1 Diabetes [PDF]

, 2009
OBJECTIVE: The purpose of this study was to examine prospectively whether renal hyperfiltration is associated with the development of microalbuminuria in patients with type 1 diabetes, after taking into account known risk factors.
Aschengrau, Ann, Ficociello, Linda H., Krolewski, Andrzej S., Perkins, Bruce A., Roshan, Bijan, Warram, James H., Weinberg, Janice M.   +6 more
core   +3 more sources

SGLT2 Inhibitors and the Diabetic Kidney [PDF]

, 2016
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression ...
Busetto, Luca, Fioretto, Paola, Rossato, Marco, Vettor, Roberto, Zambon, Alberto   +4 more
core   +1 more source

The impact of nonalcoholic fatty liver disease on renal function in children with overweight/obesity [PDF]

, 2016
The association between nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease has attracted interest and attention over recent years. However, no data are available in children.
Andreoli, Gian Marco, Bonci, Enea, Chiesa, Claudio, De Luca, Ester, DI MARTINO, Michele, Gallozzi, Alessia, Pacifico, Lucia   +6 more
core   +2 more sources

Case report: increased single-nephron estimated glomerular filtration rate in an adult patient with low birth weight

BMC Nephrology, 2020
Background Low birth weight (LBW) is associated with end-stage kidney disease and hypertension and is considered to be a surrogate marker of low nephron number. Low nephron number is hypothesized to contribute to glomerular hyperfiltration that may cause
Yuriko Shiozaki, Tomoyuki Fujikura, Shinsuke Isobe, Ibuki Takatsuka, Taichi Sato, Daiki Goto, Sayaka Ishigaki, Naro Ohashi, Hideo Yasuda   +8 more
doaj   +1 more source