New insights on glomerular hyperfiltration: a Japanese autopsy study. [PDF]
; JCI insight 2(19), e94334 (2017).
Kanzaki G+10 more
europepmc +6 more sources
Cardiorespiratory fitness and sports activities in children and adolescents with solitary functioning kidney [PDF]
Background: An increasing number of children with chronic disease require a complete medical examination to be able to practice physical activity. Particularly children with solitary functioning kidney (SFK) need an accurate functional evaluation to ...
DE CASTRO, Giovanna+10 more
core +2 more sources
Fluctuations of estimated glomerular filtration rate outside kidney disease improving global outcomes diagnostic criteria for acute kidney injury in end-stage liver disease outpatients and outcome postliver transplantation [PDF]
Background. Renal dysfunction in end-stage liver disease (ESLD) results fromsystemic conditions that affect both liver and kidney with activation of vasoconstrictor systems.
Berloco, Pasquale Bartolomeo+12 more
core +1 more source
Treatable glomerular hyperfiltration in patients with active acromegaly [PDF]
ObjectiveThe glomerular filtration rate (GFR) is increased in patients with active acromegaly. The aim of this study is to elucidate whether renal function deteriorates in patients with acromegaly and whether this deterioration is reversible after surgical remission.Design/methodsA case–control study of 48 acromegalic patients who were surgically cured
Manoj Bohara+10 more
openaire +3 more sources
From secondary to primary prevention of progressive renal disease: The case for screening for albuminuria [PDF]
From secondary to primary prevention of progressive renal disease: The case for screening for albuminuria. Many subjects nowadays present with end-stage renal failure and its attendant cardiovascular complications without known prior renal damage.
Brenner, Barry M., De Jong, Paul E.
core +1 more source
Acute kidney injury urinary biomarker time-courses. [PDF]
Factors which modify the excretion profiles of acute kidney injury biomarkers are difficult to measure. To facilitate biomarker choice and interpretation we modelled key modifying factors: extent of hyperfiltration or reduced glomerular filtration rate ...
John W Pickering, Zoltán H Endre
doaj +1 more source
Tubular reabsorption and diabetes‐induced glomerular hyperfiltration [PDF]
AbstractElevated glomerular filtration rate (GFR) is a common observation in early diabetes mellitus and closely correlates with the progression of diabetic nephropathy. Hyperfiltration has been explained to be the result of a reduced load of sodium and chloride passing macula densa, secondarily to an increased proximal reabsorption of glucose and ...
Peter Hansell+3 more
openaire +3 more sources
Introduction: The kidney deterioration, which starts in childhood often leads to end-stage renal failure in the future. Therefore, searching for an early, sensitive, and specific biomarkers became a paramount for chronic kidney disease diagnosis. The aim
Agata Będzichowska+4 more
doaj +1 more source
Glomerular hyperfiltration is a predictor of adverse cardiovascular outcomes
The association between glomerular hyperfiltration and cardiovascular events is not well known. To investigate whether glomerular hyperfiltration is independently associated with risk of adverse outcome we analyzed 8794 participants, average age 52 years enrolled in 8 prospective studies. Of these, 89% had hypertension.
Yutaka Imai+14 more
openaire +5 more sources
Diabetic Proteinuria Revisited: Updated Physiologic Perspectives
Albuminuria, a hallmark of diabetic nephropathy, reflects not only injury and dysfunction of the filtration apparatus, but is also affected by altered glomerular hemodynamics and hyperfiltration, as well as by the inability of renal tubular cells to ...
Samuel N. Heyman+5 more
doaj +1 more source