Results 61 to 70 of about 16,029 (237)

Pulmonary congestion relief by adding dapagliflozin to intravenous loop diuretic in acute heart failure patients

ESC Heart Failure, EarlyView.
Abstract Aims We aim to assess the efficacy of congestion relief and safety associated with adding SGLT2i (viz., dapagliflozin 10 mg) to intravenous loop diuretics within 24 h of hospital presentation in patients with acute heart failure (AHF). Methods and results A single‐centre open‐label clinical research study enrolled 98 patients admitted with an ...
Daniela Mocan, Maria Puschita, Diana Lungeanu, Adina Pop‐Moldovan, Luminita Pilat, Dan Darabantiu, Radu Jipa, Radu Ioan Lala   +7 more
wiley   +1 more source

Glomerular Hyperfiltration in Hypertensive Fawn-Hooded Rats

Kidney and Blood Pressure Research, 1988
The glomerular filtration rate (GFR), effective renal plasma flow (ERPF), systolic blood pressure (SBP) and urinary protein excretion (U_PV) were determined in 12-week-old male rats of the spontaneously hypertensive Fawn-Hooded (FH) strain.
Jan C. Molenaar, M. H. De Keijzer, Abraham P. Provoost   +2 more
openaire   +2 more sources

SLC12A3 Variation and Renal Function in Chinese Patients With Hypertension

Frontiers in Medicine, 2022
ObjectiveSLC12A3 (solute carrier family 12 member 3) gene variants are associated with diabetic nephropathy; however, their association with hypertensive nephropathy remains unknown.
Chin-Chou Huang, Chin-Chou Huang, Chin-Chou Huang, Chin-Chou Huang, Chia-Min Chung, Chia-Min Chung, Chih-Yu Yang, Chih-Yu Yang, Chih-Yu Yang, Hsin-Bang Leu, Hsin-Bang Leu, Hsin-Bang Leu, Hsin-Bang Leu, Po-Hsun Huang, Po-Hsun Huang, Po-Hsun Huang, Po-Hsun Huang, Liang-Yu Lin, Liang-Yu Lin, Liang-Yu Lin, Tao-Cheng Wu, Tao-Cheng Wu, Tao-Cheng Wu, Shing-Jong Lin, Shing-Jong Lin, Shing-Jong Lin, Shing-Jong Lin, Wen-Harn Pan, Wen-Harn Pan, Jaw-Wen Chen, Jaw-Wen Chen, Jaw-Wen Chen, Jaw-Wen Chen   +32 more
doaj   +1 more source

MRI‐based quantification of whole‐organ renal metabolic rate of oxygen during free‐breathing

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose Renal metabolic rate of oxygen (rMRO2) reflects the kidney's metabolic efficiency, making it a potential biomarker for early‐stage kidney disease. This study introduces an ungated, free‐breathing MRI sequence in comparison to its breath‐hold counterpart to noninvasively measure whole‐organ rMRO2.
Nada Kamona, Michael C. Langham, Rajiv S. Deshpande, Brian‐Tinh D. Vu, Mahdie Hosseini, Jeffrey Dennison, Kathryn M. Jaroszynski, Felix W. Wehrli   +7 more
wiley   +1 more source

Glomerular Hyperfiltration in Sickle Cell Disease [PDF]

Clinical Journal of the American Society of Nephrology, 2010
Sickle cell disease (SCD) is a monogenetic, chronic anemia syndrome that is caused by a point mutation in the β-globin gene and affects approximately 100,000 individuals in the United States. Approximately 4 to 5% of these individuals have or will develop stage 5 chronic kidney disease (CKD), and 0.11% of patients who are on long-term maintenance renal
openaire   +2 more sources

Nephron filtration rate and proximal tubular fluid reabsorption in the Akita mouse model of type I diabetes mellitus [v1; ref status: indexed, http://f1000r.es/yw]

F1000Research, 2013
An increase of glomerular filtration rate (hyperfiltration) is an early functional change associated with type I or type II diabetes mellitus in patients and animal models. The causes underlying glomerular hyperfiltration are not entirely clear. There is
Jurgen Schnermann, Mona Oppermann, Yuning Huang   +2 more
doaj   +1 more source

Creatinine-Based Formulae Poorly Match in the Classification of Hypofiltration or Hyperfiltration in a General Population of Adolescents: A Retrospective Analysis of a Cross-Sectional Study

Frontiers in Pediatrics, 2021
Pediatric formulae to estimate glomerular filtration rate (eGFR) give a broad range of values. Their consistency in assigning the subjects as hypofiltrating or hyperfiltrating is unknown.
Katarína Šebeková, Radana Gurecká, Radana Gurecká, Ĺubomíra Tóthová, Ĺudmila Podracká, Ĺudmila Podracká   +5 more
doaj   +1 more source

Glomerular Hyperfiltration in Diabetes: Mechanisms, Clinical Significance, and Treatment. [PDF]

J Am Soc Nephrol, 2017
An absolute, supraphysiologic elevation in GFR is observed early in the natural history in 10%–67% and 6%–73% of patients with type 1 and type 2 diabetes, respectively. Moreover, at the single-nephron level, diabetes-related renal hemodynamic alterations—as an adaptation to reduction in functional nephron mass and/or in response to prevailing metabolic
Tonneijck L, Muskiet MH, Smits MM, van Bommel EJ, Heerspink HJ, van Raalte DH, Joles JA.   +6 more
europepmc   +5 more sources

Microalbuminuria as Predictor of Early Glomerular Injury in Children and Adolescents with Sickle Cell Anaemia at Muhimbili National Hospital Dar es Salaam, Tanzania 2012 [PDF]

, 2012
Microalbuminuria (MA) is the earliest marker of various diseases affecting the renal system. Its relevance in children and adolescents with sickle cell anaemia (SCA), who are known to be prone to renal complications, has not been fully explored in our ...
Christopher, Richard
core  

The effect of a multidisciplinary weight loss program on renal circadian rhythm in obese adolescents

, 2019
Adolescent obesity is a serious health problem associated with many comorbidities. Obesity-related alterations in circadian rhythm have been described for nocturnal blood pressure and for metabolic functions.
Bruneel, Elke, De Guchtenaere, Ann, Dejonckheere, Sarah, Everaert, Karel, Keersmaekers, Laura, Pauwaert, Kim, Roggeman, Saskia, Van der Jeugt, Jolien, Vande Walle, Johan   +8 more
core   +1 more source