Results 71 to 80 of about 169,139 (203)

Clinical Relevance and Diagnostic Utility of Standard Serum Biomarkers in Advanced Chronic Kidney Disease: A Single‐Center Observational Study From Bangladesh

iLABMED, EarlyView.
This study evaluated conventional and emerging biochemical markers for assessing chronic kidney disease (CKD) progression in Bangladeshi patients elevated serum uric acid and parathyroid hormone levels, along with reduced eGFR, vitamin D, and albumin levels, were significantly associated with CKD, highlighting their potential as cost‐effective early ...
Fazlul Haque, Md. Samiul Islam, Nafsoon Rahman, Ayub Zawad, Sadia Afrin, Pulak Kanti Palit, Tanjil Hasan, Md. Isahak Ali, Shafin Ahmed, Akram Hossain, Marina Khatun, Tabassuma Marzia Prome, Md. Shah Alam, Ashekul Islam   +13 more
wiley   +1 more source

Renal function impairment in children with intestinal failure receiving parenteral nutrition: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with intestinal failure are at risk for kidney dysfunction; however, the contributing factors are not well established. We aimed to describe risk factors associated with glomerular and tubular renal dysfunction in children with intestinal failure.
Amanda M. Braga da Mata, Heitor Pons Leite, Eduardo F. Hatanaka, Mariana Janiques Barcia Magalhães Fonseca, Marta Liliane de Almeida Maia, Giovana S. G. Sabio, Maria Fernanda C. de Camargo, Paulo C. Koch Nogueira   +7 more
wiley   +1 more source

Nephron filtration rate and proximal tubular fluid reabsorption in the Akita mouse model of type I diabetes mellitus [v1; ref status: indexed, http://f1000r.es/yw]

F1000Research, 2013
An increase of glomerular filtration rate (hyperfiltration) is an early functional change associated with type I or type II diabetes mellitus in patients and animal models. The causes underlying glomerular hyperfiltration are not entirely clear. There is
Jurgen Schnermann, Mona Oppermann, Yuning Huang   +2 more
doaj   +1 more source

Efficacy and safety of combining empagliflozin in people with type 2 diabetes mellitus uncontrolled with metformin and sitagliptin: A randomised, double‐blind, multicentre, therapeutic confirmatory phase 3 clinical trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aim This study evaluated the efficacy and safety of empagliflozin 10 and 25 mg compared to placebo as add‐on treatment for people with type 2 diabetes mellitus (T2DM) uncontrolled after ≥8 weeks of treatment with metformin and sitagliptin. Materials and Methods A randomised, double‐blind, multicentre, therapeutic confirmatory, phase 3 clinical
Seung‐Hwan Lee, Kyung Ah Han, Eun‐Gyoung Hong, Jun Goo Kang, Choon Hee Chung, Jong Chul Won, Eon Ju Jeon, Jung‐Hwan Cho, Ho Chan Cho, Sin Gon Kim, Eun Seok Kang, So Hun Kim, Hae Jin Kim, In‐Kyung Jeong, Sung Wan Chun, Young Min Cho   +15 more
wiley   +1 more source

Creatinine-Based Formulae Poorly Match in the Classification of Hypofiltration or Hyperfiltration in a General Population of Adolescents: A Retrospective Analysis of a Cross-Sectional Study

Frontiers in Pediatrics, 2021
Pediatric formulae to estimate glomerular filtration rate (eGFR) give a broad range of values. Their consistency in assigning the subjects as hypofiltrating or hyperfiltrating is unknown.
Katarína Šebeková, Radana Gurecká, Radana Gurecká, Ĺubomíra Tóthová, Ĺudmila Podracká, Ĺudmila Podracká   +5 more
doaj   +1 more source

Long‐acting insulin analogues and the risk of diabetic nephropathy among patients with type 2 diabetes: A population‐based cohort study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The risk of diabetic nephropathy among patients with type 2 diabetes (T2D) can be reduced through optimal glycaemic control. It is not known if the pharmacological properties of long‐acting insulin analogues may reduce the risk of diabetic complications compared with neutral protamine Hagedorn (NPH) insulin.
Julia Brillinger, Christopher Filliter, Shahrzad Salmasi, Estefania Zapata‐Bravo, Robert W. Platt, Oriana H. Y. Yu, Kristian B. Filion   +6 more
wiley   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

SLC12A3 Variation and Renal Function in Chinese Patients With Hypertension

Frontiers in Medicine, 2022
ObjectiveSLC12A3 (solute carrier family 12 member 3) gene variants are associated with diabetic nephropathy; however, their association with hypertensive nephropathy remains unknown.
Chin-Chou Huang, Chin-Chou Huang, Chin-Chou Huang, Chin-Chou Huang, Chia-Min Chung, Chia-Min Chung, Chih-Yu Yang, Chih-Yu Yang, Chih-Yu Yang, Hsin-Bang Leu, Hsin-Bang Leu, Hsin-Bang Leu, Hsin-Bang Leu, Po-Hsun Huang, Po-Hsun Huang, Po-Hsun Huang, Po-Hsun Huang, Liang-Yu Lin, Liang-Yu Lin, Liang-Yu Lin, Tao-Cheng Wu, Tao-Cheng Wu, Tao-Cheng Wu, Shing-Jong Lin, Shing-Jong Lin, Shing-Jong Lin, Shing-Jong Lin, Wen-Harn Pan, Wen-Harn Pan, Jaw-Wen Chen, Jaw-Wen Chen, Jaw-Wen Chen, Jaw-Wen Chen   +32 more
doaj   +1 more source

Effect of empagliflozin on urinary albumin excretion and hypoxic biomarkers in early diabetic kidney disease: A randomised double‐blind, placebo‐controlled trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The precise mechanism of sodium glucose co‐transporter 2 (SGLT2) inhibitor on reno‐protective effect has been still unclear. In this study, we hypothesised that SGLT2 inhibitor prevents diabetic kidney disease via reduction of hypoxia‐induced factors.
Hisashi Makino, Masato Kasahara, Ryuzo Takashima, Shu Kasama, Naoki Ozu, Hyohun Park, Qingxing Chen, Kazuhiko Tsuruya, Mayu Tochiya, Yoko Omura‐Ohata, Tamiko Tamanaha, Michio Noguchi, Takeshi Aiba, Fumiki Yoshihara, Kiminori Hosoda   +14 more
wiley   +1 more source

Adiponectin for the treatment of diabetic nephropathy [PDF]

The Korean Journal of Internal Medicine, 2019
The metabolic burden caused by hyperglycemia can result in direct and immediate metabolic injuries, such as oxidative stress and tissue inflammation, in the kidney.
Jun Young Lee, Jae Won Yang, Byoung Geun Han, Seung Ok Choi, Jae Seok Kim   +4 more
doaj   +1 more source