Results 81 to 90 of about 16,029 (237)

Prevalence and risk factors of glomerular hyperfiltration in adults with type 2 diabetes: A population-based study [PDF]

open access: yes
Aims: Glomerular hyperfiltration characterises the earliest stage of diabetic nephropathy and predicts adverse kidney and cardiovascular outcomes. We aimed to assess the prevalence and risk factors of glomerular hyperfiltration in a population-based ...
Adriano Gatti   +94 more
core   +1 more source

Evaluation of Pediatric and Young Adult Cancer Survivors at Risk of Long‐Term Kidney Complications

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Nephrotoxic chemotherapy, nephrectomy, abdominal radiotherapy exposure, and the presence of kidney or pelvic tumors are risk factors associated with long‐term kidney complications. This study aimed to determine the prevalence of long‐term kidney complications in patients who survived pediatric and young adult cancer and were exposed
Ahmed Zeid   +6 more
wiley   +1 more source

Hyperfiltration and renal disease in glycogen storage disease, type I [PDF]

open access: yes, 1989
Hyperfiltration and renal disease in glycogen storage disease, type I. A prospective study of 14 patients (ages 6 months to 33 years) with glycogen storage disease, Type I (GSD-I) was carried out in order to define the character and frequency of renal ...
Alepa   +42 more
core   +1 more source

The Impact of Augmented Renal Clearance on the Pharmacokinetics of Levetiracetam in Critically Ill Patients: A Literature Review

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 7, Page 815-834, July 2025.
Abstract Levetiracetam is an antiseizure medication (ASM) that has several advantages over other ASMs, such as dose‐proportional pharmacokinetics, high bioavailability, and minimal drug interactions. The drug is primarily eliminated through the kidneys. Therefore, dose adjustments are necessary in patients with renal impairment or patients experiencing
Maged Kharouba   +3 more
wiley   +1 more source

Rheological Influence Upon the Glomerular Podocyte and Resultant Mechanotransduction

open access: yesKidney & Blood Pressure Research, 2015
The glomerular podocyte is exposed to numerous mechanical forces as a constituent of the glomerular filtration apparatus. This includes fluid shear stress (FSS) displaced upon the podocytic foot process's apical, lateral, and basal surfaces.
Simona Pichler Sekulic, Miroslav Sekulic
doaj   +1 more source

Fasting and postprandial kidney haemodynamic effects of empagliflozin and linagliptin in mono‐ and combination therapy compared to gliclazide in overweight people with type 2 diabetes (RACELINES): A randomised, double‐blind trial

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 7, Page 3943-3956, July 2025.
Abstract Background Sodium‐glucose cotransporter (SGLT) 2 inhibitors attenuate fasting glomerular hyperfiltration in people with type 2 diabetes (T2D). However, SGLT2‐inhibition increases glucagon levels, which facilitate postprandial hyperfiltration.
Michaël J. B. van Baar   +10 more
wiley   +1 more source

Prevalence of hyperfiltration among US youth/young adults with overweight and obesity: A population‐based association study

open access: yesObesity Science & Practice, 2019
Summary Objective Determine prevalence of hyperfiltration (high estimated glomerular filtration rate "eGFR" >95th percentile for age/sex) among youth and association with BMI classification.
Christy B. Turer   +4 more
doaj   +1 more source

Glycemia affects glomerular filtration rate in people with type 2 diabetes

open access: yesBMC Nephrology, 2019
Background In type 2 diabetes (T2DM), the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation for estimated glomerular filtration rate (eGFR) systematically underestimates the measured adjusted glomerular filtration rate (aGFR) when aGFR
E. Jennifer Weil   +3 more
doaj   +1 more source

Renal hyperfiltration and systemic blood pressure in patients with uncomplicated type 1 diabetes mellitus. [PDF]

open access: yesPLoS ONE, 2013
Patients with type 1 diabetes mellitus (DM) and renal hyperfiltration also exhibit systemic microvascular abnormalities, including endothelial dysfunction. The effect of renal hyperfiltration on systemic blood pressure (BP) is less clear.
Gary K Yang   +3 more
doaj   +1 more source

Potentially harmful advantage to athletes: a putative connection between UGT2B17 gene deletion polymorphism and renal disorders with prolonged use of anabolic androgenic steroids [PDF]

open access: yes, 2010
: BACKGROUND AND OBJECTIVE: With prolonged use of anabolic androgenic steroids (AAS), occasional incidents of renal disorders have been observed. Independently, it has also been established that there are considerable inter-individual and inter-ethnic ...
Barker, James   +5 more
core   +3 more sources

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