Prevalence and risk factors of glomerular hyperfiltration in adults with type 2 diabetes: A population-based study [PDF]
Aims: Glomerular hyperfiltration characterises the earliest stage of diabetic nephropathy and predicts adverse kidney and cardiovascular outcomes. We aimed to assess the prevalence and risk factors of glomerular hyperfiltration in a population-based ...
Adriano Gatti+94 more
core +1 more source
Evaluation of Pediatric and Young Adult Cancer Survivors at Risk of Long‐Term Kidney Complications
ABSTRACT Background Nephrotoxic chemotherapy, nephrectomy, abdominal radiotherapy exposure, and the presence of kidney or pelvic tumors are risk factors associated with long‐term kidney complications. This study aimed to determine the prevalence of long‐term kidney complications in patients who survived pediatric and young adult cancer and were exposed
Ahmed Zeid+6 more
wiley +1 more source
Hyperfiltration and renal disease in glycogen storage disease, type I [PDF]
Hyperfiltration and renal disease in glycogen storage disease, type I. A prospective study of 14 patients (ages 6 months to 33 years) with glycogen storage disease, Type I (GSD-I) was carried out in order to define the character and frequency of renal ...
Alepa+42 more
core +1 more source
Abstract Levetiracetam is an antiseizure medication (ASM) that has several advantages over other ASMs, such as dose‐proportional pharmacokinetics, high bioavailability, and minimal drug interactions. The drug is primarily eliminated through the kidneys. Therefore, dose adjustments are necessary in patients with renal impairment or patients experiencing
Maged Kharouba+3 more
wiley +1 more source
Rheological Influence Upon the Glomerular Podocyte and Resultant Mechanotransduction
The glomerular podocyte is exposed to numerous mechanical forces as a constituent of the glomerular filtration apparatus. This includes fluid shear stress (FSS) displaced upon the podocytic foot process's apical, lateral, and basal surfaces.
Simona Pichler Sekulic, Miroslav Sekulic
doaj +1 more source
Abstract Background Sodium‐glucose cotransporter (SGLT) 2 inhibitors attenuate fasting glomerular hyperfiltration in people with type 2 diabetes (T2D). However, SGLT2‐inhibition increases glucagon levels, which facilitate postprandial hyperfiltration.
Michaël J. B. van Baar+10 more
wiley +1 more source
Summary Objective Determine prevalence of hyperfiltration (high estimated glomerular filtration rate "eGFR" >95th percentile for age/sex) among youth and association with BMI classification.
Christy B. Turer+4 more
doaj +1 more source
Glycemia affects glomerular filtration rate in people with type 2 diabetes
Background In type 2 diabetes (T2DM), the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation for estimated glomerular filtration rate (eGFR) systematically underestimates the measured adjusted glomerular filtration rate (aGFR) when aGFR
E. Jennifer Weil+3 more
doaj +1 more source
Renal hyperfiltration and systemic blood pressure in patients with uncomplicated type 1 diabetes mellitus. [PDF]
Patients with type 1 diabetes mellitus (DM) and renal hyperfiltration also exhibit systemic microvascular abnormalities, including endothelial dysfunction. The effect of renal hyperfiltration on systemic blood pressure (BP) is less clear.
Gary K Yang+3 more
doaj +1 more source
Potentially harmful advantage to athletes: a putative connection between UGT2B17 gene deletion polymorphism and renal disorders with prolonged use of anabolic androgenic steroids [PDF]
: BACKGROUND AND OBJECTIVE: With prolonged use of anabolic androgenic steroids (AAS), occasional incidents of renal disorders have been observed. Independently, it has also been established that there are considerable inter-individual and inter-ethnic ...
Barker, James+5 more
core +3 more sources