Results 131 to 140 of about 153,148 (261)
ABSTRACT Introduction Acquired factor V (FV) deficiency is a rare bleeding disorder requiring careful management, especially in hemodialysis (HD) patients who regularly receive anticoagulants. We present a case of recurrent acquired FV deficiency in a dialysis patient.
Akihiko Sugino +9 more
wiley +1 more source
Introduction: Anti-glomerular basement membrane (GBM) disease is a rare cause of glomerulonephritis usually mediated by IgG antibodies and is associated with ANCA-associated glomerulonephritis in up to 50% of cases.
Ciaran Twomey Brenner +5 more
doaj +1 more source
Alterations of podocytes in a murine model of crescentic glomerulonephritis [PDF]
Recent observations suggest a central role of podocytes in crescent formation. In experimental glomerulonephritis podocytes disrupt the parietal epithelial layer and attach on its basement membrane, thus forming bridges between the tuft and Bowman's ...
Besse-Eschmann, Valérie +3 more
core
Fibroblast‐specific palladin drives kidney fibrosis via MRTF–SRF signaling
Abstract Fibrosis is a common end‐stage pathway of progressive chronic kidney diseases. Previously we demonstrated that myocardin‐related transcription factor (MRTF)–serum response factor (SRF) signaling drives the expression of fibrosis‐related molecules through actin cytoskeleton dynamics in renal fibroblasts.
Naoki Yamamoto +27 more
wiley +1 more source
Annus Mirabilis - a guide to the 6th European Lupus meeting 3-5 March 2005 [PDF]
This article has no ...
Bowman, S.J. +4 more
core
Impact of low‐dose cypermethrin exposure on health. ABSTRACT Cypermethrin, a synthetic pyrethroid widely used in agricultural land areas and also for ectoparasitic control in livestock, has been implicated in various health effects. The study was conducted to elucidate the histopathological and biochemical consequences of low‐dose cypermethrin exposure
Swarup Kumar Kundu +9 more
wiley +1 more source
An adult with kidney failure had compound‐heterozygous TMEM126B variants causing mitochondrial complex I deficiency. This expands TMEM126B to mitochondrial nephropathy and supports including mitochondrial genes in renal genetic testing.
Zachary T. Sentell +7 more
wiley +1 more source
Abstract Background Systemic lupus erythematosus (SLE) is an autoimmune disease with a heterogenous clinical picture. This study aimed to link genetic SLE predisposition with relevant clinical manifestations. Method Datasets best corresponding to the 11 American College of Rheumatology 1982 (ACR‐82) classification criteria for SLE in a large, public ...
Sarah Reid +16 more
wiley +1 more source
Nicotinamide Attenuates Complement and Coagulation Pathways and Resultant Renal Fibrosis
The coagulation and complement cascades were elevated in the pathogenesis of chronic kidney disease (CKD) and may contribute to both kidney injury and cardiovascular risk. These excessive signals and the associated innate immune responses were suppressed by the NAD+ precursor nicotinamide (NAM).
Saori Kin +6 more
wiley +1 more source

