Results 151 to 160 of about 99,939 (269)
British Journal of Haematology, Volume 208, Issue 6, Page 2059-2068, June 2026.Renal dysfunction represents a possible underrecognized complication of symptomatic WM; this condition correlates with adverse global and disease‐specific clinical outcomes. Summary The prognostic significance of impaired renal function in Waldenström macroglobulinaemia (WM) remains poorly defined.
Nicolò Danesin +27 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 11, Page 2874-2889, June 2026.Abstract Background and Purpose Overactivation of the alternative pathway (AP) underlies several diseases. Iptacopan is an oral, first‐in‐class, highly potent specific inhibitor of factor B, a key AP protease. Experimental Approach The analysis included data from two phase 1 randomised, volunteer‐blinded, placebo‐controlled studies: Study 1, a single ...
Irina Baltcheva +5 more
wiley +1 more source
Clinical Transplantation, Volume 40, Issue 6, June 2026.ABSTRACT Introduction The effects of induction therapy with the anti‐CD52 monoclonal antibody alemtuzumab on age‐specific outcomes following kidney transplantation (KT) remain inadequately studied. This study aimed to analyze the comparative safety and efficacy of single‐dose alemtuzumab induction in deceased donor (DD) KT recipients according to ...
Alex Ng +6 more
wiley +1 more source
Clinical Transplantation, Volume 40, Issue 6, June 2026.ABSTRACT Donor derived cell‐free DNA (dd‐cfDNA) has become a useful biomarker for monitoring of kidney transplant rejection, however utilization after rejection is not well established. We conducted a retrospective cohort study of 64 kidney transplant recipients (KTRs) with biopsy‐proven rejection and concomitant dd‐cfDNA monitoring.
Lauren Schumacher +7 more
wiley +1 more source
Kidney: Subacute Glomerulonephritis
, 1900 Subacute glomerulonephritis, as with ...
MUSC Department of Pathology and Laboratory Medicine
core
Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease
Immunology, Volume 178, Issue 2, Page 218-230, June 2026.This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley +1 more source
The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley +1 more source
Viruses and Glomerulonephritis [PDF]
Nephron, 2008 P, Ronco, P, Verroust, L, Morel-Maroger
openaire +4 more sources
Case Report: Successful treatment of <i>Bartonella henselae</i>-associated crescentic glomerulonephritis in renal transplant recipient. [PDF]
Front Med (Lausanne)Pierson S +9 more
europepmc +1 more source