Results 131 to 140 of about 132,152 (259)
Arthritis &Rheumatology, Volume 78, Issue 4, Page 880-895, April 2026.Objective Systemic lupus erythematosus (SLE) is characterized by increased Type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama +16 more
wiley +1 more source
LIGHT AND ELECTRON MICROSCOPIC STUDY OF BIOPSIES FROM THIRTY‐THREE HUMAN RENAL ALLOGRAFTS AND AN ISOGRAFT 13/
, 1966 ALLEN +27 more
core +1 more source
Arthritis &Rheumatology, Volume 78, Issue 4, Page 970-975, April 2026.Objective Ear, nose, and throat (ENT) manifestations are common in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). There is an unmet need for drugs to target these manifestations. Granuloma formation is characteristic of proteinase 3 (PR3)–AAV. In a zebrafish model, niclosamide inhibits PR3‐induced granuloma formation.
Benjamin Lim +4 more
wiley +1 more source
Brain and Behavior, Volume 16, Issue 4, April 2026.This resting‐state functional MRI (rs‐fMRI) study identifies distinct patterns of spontaneous brain activity in patients with diabetic kidney disease (DKD) compared to non‐diabetic kidney disease (non‐DKD). Altered functional connectivity (FC) between the putamen and specific brain regions implicates its potential significance as a key neural target in
Xiwen Lei +8 more
wiley +1 more source
Lupus glomerulonephritis and other autoimmune glomerulonephritis
Revista de Nefrología, Diálisis y Trasplante, 2014 La glomerulonefritis es un término empleado para expresar la proliferación e inflamación endocapilar del glomérulo renal, que clínicamente puede manifestarse de numerosas formas e incluso permanecer asintomática.
María Ruiz-Olivares +3 more
doaj
Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.ABSTRACT Urolithiasis, a condition characterized by the formation of calcium oxalate stones in the urinary tract, remains a significant clinical challenge due to the limited availability of effective preventive therapies. This study investigated the antiurolithic potential of different preparations from Eugenia mattosii, a plant rich in phenolic ...
Bianca Letícia Maciél +8 more
wiley +1 more source
A Case Study and Review of the Literature on IgA Nephropathy in Crohn's Disease
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT IgA nephropathy (IgAN) is the most frequently reported glomerular disease associated with inflammatory bowel disease (IBD), particularly Crohn's disease (CD), although pediatric cases remain rare. We report IgAN in a 16‐year‐old male with CD following intestinal surgery and during long‐term infliximab therapy, with renal impairment occurring ...
Giovanna Fernanda Vazzana +6 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 4, April 2026.Successful steroid‐free remission of MPO‐ANCA‐negative eosinophilic granulomatosis with polyangiitis (EGPA). Due to concurrent poorly controlled diabetes, standard high‐dose glucocorticoids were avoided. Low‐dose mepolizumab (100 mg/month) monotherapy was initiated, resulting in rapid eosinophil reduction, resolution of pulmonary infiltrates, and ...
Suzuka Matsuoka +7 more
wiley +1 more source
Crescentic glomerulonephritis [PDF]
Nephrology Dialysis Transplantation, 2001 J C, Jennette, D B, Thomas
openaire +2 more sources
Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.In a prospective cohort of patients with definite Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), multiple drug hypersensitivity syndrome (MDHS) was associated with increased disease severity and a higher frequency of human leukocyte antigen (HLA) risk alleles.
Derya Ünal +22 more
wiley +1 more source