Results 81 to 90 of about 175,446 (337)

Pauci-Immune Crescentic Glomerulonephritis: An ANCA-Associated Vasculitis

open access: yesBioMed Research International, 2015
Rapidly progressive glomerulonephritis (RPGN) is a syndrome signified by a precipitous loss of renal function, with features of glomerulonephritis including dysmorphic erythrocyturia and glomerular proteinuria.
Rafeel Syed   +3 more
semanticscholar   +1 more source

The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice [PDF]

open access: yes, 1996
MRL/MP-lpr/lpr (MRL/lpr) mice develop a spontaneous autoimmune disease. Serum from these mice contained significantly higher concentrations of nitrite/nitrate than serum from age-matched control MRL/MP-+/+ (MRL/+), BALB/c or CBA/6J mice.
Feng, G.J.   +4 more
core   +3 more sources

From clinical observations to molecular insights: Decoding immune checkpoint inhibitors‐induced prostatitis

open access: yesVIEW, EarlyView.
Immune checkpoint inhibitors (ICIs), an innovative class of cancer therapeutics, may elevate the risk of prostate inflammation (prostatitis) in a subset of male patients. Our investigation demonstrated that ICIs can induce inflammatory responses in prostate tissue; however, selectively targeting specific inflammatory pathways may potentially mitigate ...
Peng Luo   +9 more
wiley   +1 more source

ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis

open access: yesCase Reports in Nephrology
Kidney complications can occur due to infective endocarditis, one of which is glomerulonephritis. Most often, an immune complex or complement-mediated glomerulonephritis is seen on kidney biopsy.
Camille Ng   +5 more
doaj   +1 more source

Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice.

open access: yesJournal of Clinical Investigation, 2002
Antineutrophil cytoplasmic autoantibodies (ANCAs) are identified in the circulation of approximately 80% of patients with pauci-immune necrotizing and crescentic glomerulonephritis and systemic small vessel vasculitis, such as microscopic polyangiitis ...
Hong Xiao   +8 more
semanticscholar   +1 more source

Simultaneous Occurrence of Systemic Lupus Erythematosus, Rheumatoid Arthritis, Hashimoto’s Thyroiditis and Membranous Glomerulonephritis

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2014
Introduction: Membranous glomerulonephritis is commonly described in systemic lupus erythematosus (SLE) and hypothyroidism. Clinical presentation: We report a case of a 40-year-old woman who presented with a membranous glomerulonephritis associated with
Lilia Baili   +6 more
doaj   +1 more source

Autoimmunity and glomerulonephritis [PDF]

open access: yesPostgraduate Medical Journal, 1992
Autoimmunity is now unequivocally regarded as the predominant pathogenic process underlying most forms of primary and secondary glomerulonephritis in humans. Most of the investigations so far have been focused upon humoral mechanisms. Consequently, the role of cell-mediated immunity in nephritis is still incompletely understood.
Jörgen Wieslander   +3 more
openaire   +2 more sources

The in silico macrophage: toward a better understanding of inflammatory disease [PDF]

open access: yes, 2011
Macrophages function as sentinel, cell-regulatory hubs capable of initiating, perpetuating and contributing to the resolution of an inflammatory response, following their activation from a resting state. Highly complex and varied gene expression programs
Ghazal, Peter   +3 more
core   +3 more sources

Lower time‐averaged serum uric acid was associated with increased mortality in peritoneal dialysis patients

open access: yesTherapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 479-490, June 2025.
Abstract Background The relationship between time‐averaged serum uric acid (TA‐SUA) levels and prognosis in peritoneal dialysis (PD) patients are rarely discussed. Methods This was a retrospective cohort study. PD patients recruited from January 1, 2011, to December 31, 2020, were included.
Lu Li   +8 more
wiley   +1 more source

Avoiding early diagnosis

open access: yes
Journal of General and Family Medicine, EarlyView.
Takao Wakabayashi   +5 more
wiley   +1 more source

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