Results 81 to 90 of about 175,446 (337)
Pauci-Immune Crescentic Glomerulonephritis: An ANCA-Associated Vasculitis
Rapidly progressive glomerulonephritis (RPGN) is a syndrome signified by a precipitous loss of renal function, with features of glomerulonephritis including dysmorphic erythrocyturia and glomerular proteinuria.
Rafeel Syed+3 more
semanticscholar +1 more source
The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice [PDF]
MRL/MP-lpr/lpr (MRL/lpr) mice develop a spontaneous autoimmune disease. Serum from these mice contained significantly higher concentrations of nitrite/nitrate than serum from age-matched control MRL/MP-+/+ (MRL/+), BALB/c or CBA/6J mice.
Feng, G.J.+4 more
core +3 more sources
Immune checkpoint inhibitors (ICIs), an innovative class of cancer therapeutics, may elevate the risk of prostate inflammation (prostatitis) in a subset of male patients. Our investigation demonstrated that ICIs can induce inflammatory responses in prostate tissue; however, selectively targeting specific inflammatory pathways may potentially mitigate ...
Peng Luo+9 more
wiley +1 more source
ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis
Kidney complications can occur due to infective endocarditis, one of which is glomerulonephritis. Most often, an immune complex or complement-mediated glomerulonephritis is seen on kidney biopsy.
Camille Ng+5 more
doaj +1 more source
Antineutrophil cytoplasmic autoantibodies (ANCAs) are identified in the circulation of approximately 80% of patients with pauci-immune necrotizing and crescentic glomerulonephritis and systemic small vessel vasculitis, such as microscopic polyangiitis ...
Hong Xiao+8 more
semanticscholar +1 more source
Introduction: Membranous glomerulonephritis is commonly described in systemic lupus erythematosus (SLE) and hypothyroidism. Clinical presentation: We report a case of a 40-year-old woman who presented with a membranous glomerulonephritis associated with
Lilia Baili+6 more
doaj +1 more source
Autoimmunity and glomerulonephritis [PDF]
Autoimmunity is now unequivocally regarded as the predominant pathogenic process underlying most forms of primary and secondary glomerulonephritis in humans. Most of the investigations so far have been focused upon humoral mechanisms. Consequently, the role of cell-mediated immunity in nephritis is still incompletely understood.
Jörgen Wieslander+3 more
openaire +2 more sources
The in silico macrophage: toward a better understanding of inflammatory disease [PDF]
Macrophages function as sentinel, cell-regulatory hubs capable of initiating, perpetuating and contributing to the resolution of an inflammatory response, following their activation from a resting state. Highly complex and varied gene expression programs
Ghazal, Peter+3 more
core +3 more sources
Abstract Background The relationship between time‐averaged serum uric acid (TA‐SUA) levels and prognosis in peritoneal dialysis (PD) patients are rarely discussed. Methods This was a retrospective cohort study. PD patients recruited from January 1, 2011, to December 31, 2020, were included.
Lu Li+8 more
wiley +1 more source