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Medical Clinics of North America, 1984
The observation has been made that after any of a variety of initial renal injuries, nephron units that have been spared undergo structural and functional compensations. The functional compensation of increased perfusion of residual nephrons may present deleterious, maladaptive stresses to those surviving nephrons and lead to their ultimate destruction.
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The observation has been made that after any of a variety of initial renal injuries, nephron units that have been spared undergo structural and functional compensations. The functional compensation of increased perfusion of residual nephrons may present deleterious, maladaptive stresses to those surviving nephrons and lead to their ultimate destruction.
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A WEARABLE ARTIFICIAL GLOMERULUS
ASAIO Journal, 1979We have shown that hemofiltration can be conducted for 16 hrs/day for more than 3 continuous days by connecting an Amicon 0.2 M2 hemofilter to an arteriovenous shunt. We can produce over 8 ml/min of ultrafiltrate with no external pump, and this ultrafiltrate can be replaced by having the patient drink an electrolyte-glucose solution.
M S, Neff, S, Sadjadi, R, Slifkin
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The Mesangium of the Renal Glomerulus
Scottish Medical Journal, 1971The transport of injected thorotrast across the glomerulus of the frog kidney was studied following destruction of its mesangium. The results suggest that the mesangium contributes to the physiological integrity of the glomerular basement membrane and may therefore be a factor in the aetiology of glomerulonephritis.
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Transplantation, 2017
Organ-on-chip is an emerging technology for drug testing, disease modelling, and organ function modeling. Despite development of nephron-on-chip1 and its components, such as proximal-tubule-on-chip,2 glomerulus-on-chip has not been realized mostly due to lack of functional podocytes.
Ashammakhi, Nureddin +2 more
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Organ-on-chip is an emerging technology for drug testing, disease modelling, and organ function modeling. Despite development of nephron-on-chip1 and its components, such as proximal-tubule-on-chip,2 glomerulus-on-chip has not been realized mostly due to lack of functional podocytes.
Ashammakhi, Nureddin +2 more
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Effects of aging on the renal glomerulus
The American Journal of Medicine, 1986The biologic price of aging includes progressive deterioration of renal function and structure. After the age of 30, glomerular filtration and renal blood flow rates decline in a linear fashion, so that values in octagenarians are only half to two thirds those measured in young adults.
S, Anderson, B M, Brenner
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2015
Abstract The glomerulus performs its functions with three major cell types. Endothelial cells and visceral epithelial cells (podocytes) lie on the inside and outside of the glomerular basement membrane, and together these three structures form the glomerular filtration barrier. Mesangial cells sit in the axial region.
Marlies Elger, Wilhelm Kriz
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Abstract The glomerulus performs its functions with three major cell types. Endothelial cells and visceral epithelial cells (podocytes) lie on the inside and outside of the glomerular basement membrane, and together these three structures form the glomerular filtration barrier. Mesangial cells sit in the axial region.
Marlies Elger, Wilhelm Kriz
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2015
The glomeruli of kidney are selective filtering corpuscles composed of a capillary network, podocytes, and mesangial cells (panel a). The glomerular basement membrane (GBM) is situated between capillary endothelia and podocytes (cf. Fig. 107). All three cell types and the GBM are important for the ultrafiltration of plasma.
Margit Pavelka, Jürgen Roth
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The glomeruli of kidney are selective filtering corpuscles composed of a capillary network, podocytes, and mesangial cells (panel a). The glomerular basement membrane (GBM) is situated between capillary endothelia and podocytes (cf. Fig. 107). All three cell types and the GBM are important for the ultrafiltration of plasma.
Margit Pavelka, Jürgen Roth
openaire +1 more source

