Results 121 to 130 of about 51,931 (337)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Touch influences perceived gloss
Identifying an object’s material properties supports recognition and action planning: we grasp objects according to how heavy, hard or slippery we expect them to be.
Adams, W., Kerrigan, I.S., Graf, Erich
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Studies on Gloss of Printed Surfaces [PDF]
This scientific work investigates the gloss of printed metallized surfaces. In the first part of the study, three different gloss meters - the micro-TRI-gloss by Byk Gardner, the IQ-S by Rhopoint, and the Surface Reflectance Analyzer by Canon - are ...
Weber, Carl Fridolin
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The surface of the wood substrate is needed to be sanded before applying required amount of lacquer. The main purpose of this study is to find out if it is possible to replace the sanding process of wood substrate before applying a lac-quer, and to ...
Pavlo Bekhta +2 more
doaj +1 more source
Color perception of 3D objects: Constancy with respect to variation in surface gloss
1# What determines the color appearance of real objects viewed under natural conditions? The light reflected from different locations on a single object can vary enormously.
David H. Brainard +2 more
core

