Results 211 to 220 of about 62,467 (291)

Refining the timing of Middle Pleistocene (MIS 12 to MIS 6) ice advances into northern central Europe: sedimentological analysis and single‐grain luminescence dating of glaciotectonic complexes and tunnel‐valley fills

open access: yesBoreas, EarlyView.
We summarize the current state of knowledge on the age of the Middle Pleistocene ice advances into northern central Europe and provide 25 new single‐grain feldspar luminescence ages of Elsterian and Saalian glacigenic sediments to constrain the age of the ice advances and their tentative correlation with marine isotope stages/substages.
Niklas von Soest   +10 more
wiley   +1 more source

Defining AV2‐1 as a novel pharmacological probe to target human and rodent TRPV2

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Transient receptor potential vanilloid 2 (TRPV2) is a non‐selective cation channel implicated in immune cell functions. However, progress in understanding TRPV2 has been limited by a lack of potent and selective pharmacological tools, particularly those targeting the human variant. We aimed to identify and characterise a
Andrea Leipe   +6 more
wiley   +1 more source

Antibacterial Activity of Fructose-Stabilized Silver Nanoparticles Produced by Direct Current Atmospheric Pressure Glow Discharge towards Quarantine Pests. [PDF]

open access: yesNanomaterials (Basel), 2018
Dzimitrowicz A   +8 more
europepmc   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber   +8 more
wiley   +1 more source

Utility of Urinary Extracellular Vesicles for Colorectal Cancer: Comparison of DNA Quality and MRD Detection

open access: yesCancer Science, EarlyView.
Urinary EVs provide highly pure vesicles with superior DNA quality, making them a robust and completely non‐invasive source for molecular profiling. Urinary EV‐DNA–based MRD assessment shows significant prognostic value and may serve as a practical tool for postoperative monitoring and risk stratification in colorectal cancer.
Shintaro Kanaka   +14 more
wiley   +1 more source

Uncovering a previously unknown function of polyphosphate in polyadenylated RNA‐induced amyloidogenesis of Hfq

open access: yesThe FEBS Journal, EarlyView.
Polyphosphate interaction with Hfq and RNA drives phase separation and amyloid self‐assembly, uncovering a previously unrecognized role for polyP in bacterial stress responses. Our findings reveal new insights into the molecular mechanisms of RNA‐mediated phase separation, highlighting the role of polyP as a key modulator of this process. Polyphosphate
Kevin Mosca   +5 more
wiley   +1 more source

Redefinition of Stemonosudis intermedia (Ege, 1933) and description of a new species from the western Atlantic Ocean (Aulopiformes: Paralepididae)

open access: yesJournal of Fish Biology, EarlyView.
Abstract We examined specimens of slender barracudina in the genus Stemonosudis collected from the western Atlantic Ocean. Investigation revealed that seven specimens represent the first adult records of Stemonosudis intermedia (Ege, 1933), previously known only from juveniles. We redescribed S.
Hsuan‐Ching Ho, Katherine E. Bemis
wiley   +1 more source

Unravelling the skin of the nurse shark: A morphological description of the placoid scales of Ginglymostoma cirratum

open access: yesJournal of Fish Biology, EarlyView.
Abstract Ginglymostoma cirratum, commonly known as the nurse shark, is a nocturnally active benthic shark, often found in western and eastern Atlantic waters. Although this shark has been well explored in many biological aspects, few studies have thoroughly examined the morphology of its dermal denticles (or placoid scales).
Danilo P. Lima   +7 more
wiley   +1 more source

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